Recombinant
RabMAb

Anti-Estriol antibody [EPPTXR3] (ab150407)

Overview

  • Product name
    Anti-Estriol antibody [EPPTXR3]
    See all Estriol primary antibodies
  • Description
    Rabbit monoclonal [EPPTXR3] to Estriol
  • Tested applications
    Suitable for: ELISAmore details
  • Immunogen

    KLH conjugated Estriol.

  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Applications

Our Abpromise guarantee covers the use of ab150407 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use a concentration of 0.075 µg/ml.

Target

  • Relevance
    Estriol is a hydroxylated metabolite of ESTRADIOL or ESTRONE that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is the main estrogen in the blood and urine of pregnant females. During pregnancy, large amount of estriol is produced by the placenta. Serum estriol determinations reflect the status of the fetus and are used to evaluate fetal distress and placental function. Estriol increases until term, reaches a plateau at the 40th week of gestation and then declines. Isomers with inversion of the hydroxyl group or groups are called epiestriol. It is used in the treatment of osteoporosis in combination with Vitamin D. Its expression also seems to be one of the direct causes of preterm labour, together with cervical ultrasound mesurements and espression of Foetal Fibronectin.
  • Cellular localization
    Secreted
  • Alternative names
    • E3 antibody

Images

  • 2 ug/ml of goat anti-rabbit IgG was coated into 96-wells. After blocking with 1%BSA, serial dilution of Estriol (0, 0.1, 0.5, 2, 5, 10, 20, and 50ng/ml) were added together with HRP conjugated Estriol (1/100) and 0.075 ug/ml of ab150407 into 96-wells. After washing, TMB substrate was used to develop the color.
  • 2 ug/ml of goat anti-rabbit IgG was coated into 96-wells. After blocking with 1% BSA, 20ng/ml of various buffer containing Estriol, Estradiol, Estrone, 16-Epiestriol, Estriol 3-sulfate, 16-Hydroxyestrone , or PBS buffer only were added together with HRP conjugated Estriol (1/100) and 0.075 ug/ml of ab150407 into 96- wells. After washing, TMB substrate was used to develop the color.

References

ab150407 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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