Anti-Estrogen Inducible Protein pS2 antibody [SPM313], prediluted (ab54331)

Overview

  • Product nameAnti-Estrogen Inducible Protein pS2 antibody [SPM313], prediluted
    See all Estrogen Inducible Protein pS2 primary antibodies
  • Description
    Mouse monoclonal [SPM313] to Estrogen Inducible Protein pS2, prediluted
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cynomolgus Monkey
  • Immunogen

    Synthetic peptide: KGCCFDDTVR GVPWCFYPNT IDVPPEEECE F, corresponding to C terminal amino acids 54-84 of Human Estrogen Inducible Protein pS2

  • Epitopeab54331 reacts with an epitope located in the region encoded by aa 54-84.
  • Positive control
    • Normal stomach or breast carcinoma tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab54331 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: Ready to use.
    No special pretreatment is required for histochemical staining of formalin/paraffin tissues.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionStabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine.
    • Tissue specificityFound in stomach, with highest levels in the upper gastric mucosal cells (at protein level). Detected in goblet cells of the small and large intestine and rectum, small submucosal glands in the esophagus, mucous acini of the sublingual gland, submucosal glands of the trachea, and epithelial cells lining the exocrine pancreatic ducts but not in the remainder of the pancreas (at protein level). Scattered expression is detected in the epithelial cells of the gallbladder and submucosal glands of the vagina, and weak expression is observed in the bronchial goblet cells of the pseudostratified epithelia in the respiratory system (at protein level). Detected in urine (at protein level). Strongly expressed in breast cancer but at low levels in normal mammary tissue. It is regulated by estrogen in MCF-7 cells. Strong expression found in normal gastric mucosa and in the regenerative tissues surrounding ulcerous lesions of gastrointestinal tract, but lower expression found in gastric cancer (at protein level).
    • Sequence similaritiesContains 1 P-type (trefoil) domain.
    • Cellular localizationSecreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • BCEI antibody
      • Breast cancer estrogen inducible protein antibody
      • Breast cancer estrogen inducible sequence antibody
      • Breast cancer estrogen-inducible protein antibody
      • D21S21 antibody
      • Gastrointestinal trefoil protein antibody
      • Gastrointestinal trefoil protein pS2 antibody
      • hP1.A antibody
      • HP1A antibody
      • HPS 2 antibody
      • HPS2 antibody
      • pNR 2 antibody
      • PNR-2 antibody
      • pNR2 antibody
      • Polypeptide P1.A antibody
      • Protein pS2 antibody
      • PS 2 antibody
      • pS2 antibody
      • pS2 protein antibody
      • TFF 1 antibody
      • TFF1 antibody
      • TFF1_HUMAN antibody
      • Trefoil factor 1 antibody
      see all

    Anti-Estrogen Inducible Protein pS2 antibody [SPM313], prediluted images

    • Ab54331 ready to use staining human breast carcinoma tissue; formalin fixed, paraffin embedded.

    References for Anti-Estrogen Inducible Protein pS2 antibody [SPM313], prediluted (ab54331)

    This product has been referenced in:
    • Bohn OL  et al. Biomarker profile in breast carcinomas presenting with bone metastasis. Int J Clin Exp Pathol 3:139-46 (2009). IHC-P ; Human . Read more (PubMed: 20126581) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"