Anti-Estrogen Related Receptor beta antibody (ab19331)
Key features and details
- Rabbit polyclonal to Estrogen Related Receptor beta
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
Overview
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Product name
Anti-Estrogen Related Receptor beta antibody -
Description
Rabbit polyclonal to Estrogen Related Receptor beta -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details
Unsuitable for: ICC/IF -
Species reactivity
Reacts with: Rat -
Immunogen
Synthetic peptide:
DYELSQRHEEPRR
, corresponding to amino acids 376-388 of Mouse Estrogen Related Receptor beta. -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservative: 0.05% Sodium azide
Constituents: PBS, 0.1% BSA -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab19331 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 2 µg/ml. Detects a band of approximately 48 kDa (predicted molecular weight: 48 kDa).
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Notes |
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WB
Use a concentration of 2 µg/ml. Detects a band of approximately 48 kDa (predicted molecular weight: 48 kDa). |
Target
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Function
Nuclear receptor, may regulate ESR1 transcriptional activity. -
Involvement in disease
Defects in ESRRB are the cause of deafness autosomal recessive type 35 (DFNB35) [MIM:608565]. DFNB35 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. -
Sequence similarities
Belongs to the nuclear hormone receptor family. NR3 subfamily.
Contains 1 nuclear receptor DNA-binding domain. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 299210 Rat
- SwissProt: P11475 Rat
- Unigene: 104984 Rat
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Alternative names
- Err 2 antibody
- ERR b antibody
- ERR B2 antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (12)
ab19331 has been referenced in 12 publications.
- Avsec Ž et al. Base-resolution models of transcription-factor binding reveal soft motif syntax. Nat Genet 53:354-366 (2021). PubMed: 33603233
- Ni Y et al. Interruption of neutrophil extracellular traps formation dictates host defense and tubular HOXA5 stability to augment efficacy of anti-Fn14 therapy against septic AKI. Theranostics 11:9431-9451 (2021). PubMed: 34646379
- Fan YL et al. A function of fascin1 in the colony formation of mouse embryonic stem cells. Stem Cells N/A:N/A (2020). PubMed: 32379912
- Hao L et al. ERR? suppression by Sirt6 alleviates cholestatic liver injury and fibrosis. JCI Insight 5:N/A (2020). PubMed: 32701506
- Wang Y et al. ET-1 regulates the human umbilical vein endothelial cell cycle by adjusting the ERß/FOXN1 signaling pathway. Ann Transl Med 8:1499 (2020). PubMed: 33313244