Anti-Estrogen Related Receptor gamma antibody (ab77690)

Overview

  • Product name
    Anti-Estrogen Related Receptor gamma antibody
    See all Estrogen Related Receptor gamma primary antibodies
  • Description
    Goat polyclonal to Estrogen Related Receptor gamma
  • Specificity
    ab77690 is expected to recognise the reported isoform NP_001429.2.
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Dog, Chimpanzee, Rhesus monkey
  • Immunogen

    Synthetic peptide:

    CRMSNKDRHIDS

    , corresponding to internal sequence amino acids 22-33 of Human Estrogen Related Receptor gamma (NP_001429.2).

  • Positive control
    • Human Brain (Cerebellum) and Breast lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab77690 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notes
    Peptide ELISA: Antibody detection limit dilution 1/16000.
    WB: Use at a concentration of 0.2 - 0.6 µg/ml. Detects a band of approximately 51 kDa (predicted molecular weight: 51 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements.
    • Tissue specificity
      Expressed in the heart, kidney, brain, lung, bone marrow, adrenal gland, trachea, spinal cord and thyroid gland.
    • Sequence similarities
      Belongs to the nuclear hormone receptor family. NR3 subfamily.
      Contains 1 nuclear receptor DNA-binding domain.
    • Developmental stage
      Expressed at high levels in fetal brain and also in the fetal kidney, lung and liver.
    • Post-translational
      modifications
      Sumoylation on Lys-40 is enhanced by phosphorylation at Ser-45 and represses transcriptional activity.
      Phosphorylation on Ser-45 enhances sumoylation on Lys-40 thus repressing transcriptional activity.
    • Cellular localization
      Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • DKFZp781L1617 antibody
      • ERR 3 antibody
      • ERR G2 antibody
      • ERR gamma 2 antibody
      • ERR gamma-2 antibody
      • ERR3 antibody
      • ERR3_HUMAN antibody
      • ERRG 2 antibody
      • ERRG2 antibody
      • ERRgamma antibody
      • ESRRG antibody
      • Estrogen receptor related protein 3 antibody
      • Estrogen receptor-related protein 3 antibody
      • Estrogen-related receptor gamma antibody
      • FLJ16023 antibody
      • KIAA0832 antibody
      • NR3B3 antibody
      • Nuclear receptor subfamily 3 group B member 3 antibody
      see all

    Images

    • Anti-Estrogen Related Receptor gamma antibody (ab77690) at 0.2 µg/ml + Human Breast lysate (in RIPA buffer) at 35 µg

      Predicted band size : 51 kDa
      Observed band size : 51 kDa

    References

    ab77690 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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