Overview

  • Product nameAnti-Estrogen Related Receptor gamma antibody
    See all Estrogen Related Receptor gamma primary antibodies
  • Description
    Rabbit polyclonal to Estrogen Related Receptor gamma
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide conjugated to KLH and selected from the center region of Human Estrogen Related Receptor gamma.

  • Positive control
    • 293 cell line lysate; mouse spleen tissue lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab82319 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Detects a band of approximately 55 kDa (predicted molecular weight: 51 kDa).
ELISA 1/1000.

Target

  • FunctionOrphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements.
  • Tissue specificityExpressed in the heart, kidney, brain, lung, bone marrow, adrenal gland, trachea, spinal cord and thyroid gland.
  • Sequence similaritiesBelongs to the nuclear hormone receptor family. NR3 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • Developmental stageExpressed at high levels in fetal brain and also in the fetal kidney, lung and liver.
  • Post-translational
    modifications
    Sumoylation on Lys-40 is enhanced by phosphorylation at Ser-45 and represses transcriptional activity.
    Phosphorylation on Ser-45 enhances sumoylation on Lys-40 thus repressing transcriptional activity.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp781L1617 antibody
    • ERR 3 antibody
    • ERR G2 antibody
    • ERR gamma 2 antibody
    • ERR gamma-2 antibody
    • ERR3 antibody
    • ERR3_HUMAN antibody
    • ERRG 2 antibody
    • ERRG2 antibody
    • ERRgamma antibody
    • ESRRG antibody
    • Estrogen receptor related protein 3 antibody
    • Estrogen receptor-related protein 3 antibody
    • Estrogen-related receptor gamma antibody
    • FLJ16023 antibody
    • KIAA0832 antibody
    • NR3B3 antibody
    • Nuclear receptor subfamily 3 group B member 3 antibody
    see all

Anti-Estrogen Related Receptor gamma antibody images

  • Anti-Estrogen Related Receptor gamma antibody (ab82319) at 1/50 dilution (purified) + mouse spleen lysate at 35 µg

    Predicted band size : 51 kDa
    Observed band size : 55 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 14.5 kDa,25 kDa. We are unsure as to the identity of these extra bands.
  • Anti-Estrogen Related Receptor gamma antibody (ab82319) at 1/50 dilution (purified) + 293 cell lysate at 35 µg

    Predicted band size : 51 kDa
    Observed band size : 55 kDa (why is the actual band size different from the predicted?)

References for Anti-Estrogen Related Receptor gamma antibody (ab82319)

This product has been referenced in:
  • Luo Y  et al. Estrogen-related receptor ? (ERR?) regulates oxygen-dependent expression of voltage-gated potassium (K+) channels and tissue kallikrein during human trophoblast differentiation. Mol Endocrinol 27:940-52 (2013). Read more (PubMed: 23584901) »
  • Karamanlidis G  et al. Defective DNA replication impairs mitochondrial biogenesis in human failing hearts. Circ Res 106:1541-8 (2010). Read more (PubMed: 20339121) »

See all 2 Publications for this product

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"