General notesab94289 is a 293T cell transfected lysate in which Human Estrogen Sulfotransferase has been transiently over-expressed using a pCMV-Estrogen Sulfotransferase plasmid. The lysate is provided in 1X Sample Buffer.
Note: For more details about how the transfected lysate was prepared view preparation notes
BackgroundFunction: May control the level of the estrogen receptor by sulfurylating free estradiol. Maximally sulfates beta-estradiol and estrone at concentrations of 20 nM. Also sulfates dehydroepiandrosterone, pregnenolone, ethinylestradiol, equalenin, diethylstilbesterol and 1-naphthol, at significantly higher concentrations; however, cortisol, testosterone and dopamine are not sulfated.
Tissue specificity: Liver, intestine and at lower level in the kidney.
Similarity: Belongs to the sulfotransferase 1 family.