Overview

  • Product name
  • Description
    Rabbit polyclonal to ETFA
  • Tested applications
    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 1-232 of Human ETFA

  • Positive control
    • A431 whole cell lysate, HeLa whole cell lysate, HeLa cells, Mouse C2C12 xenograft, Human colon carcinoma tissue
  • General notes
    Keep as a concentrated solution

Properties

Applications

Our Abpromise guarantee covers the use of ab126131 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 35 kDa.
IHC-P 1/100 - 1/1000.
ICC/IF 1/100 - 1/1000.

Target

  • Function
    The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).
  • Involvement in disease
    Glutaric aciduria 2A
  • Sequence similarities
    Belongs to the ETF alpha-subunit/FixB family.
  • Domain
    Domain I shares an identical polypeptide fold with the beta subunit ETFB though there is no sequence similarity.
  • Post-translational
    modifications
    The N-terminus is blocked.
  • Cellular localization
    Mitochondrion matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • Alpha ETF antibody
    • Alpha-ETF antibody
    • Electron transfer flavoprotein alpha polypeptide antibody
    • Electron transfer flavoprotein alpha subunit antibody
    • Electron transfer flavoprotein subunit alpha mitochondrial antibody
    • Electron transfer flavoprotein subunit alpha, mitochondrial antibody
    • Electron transferring flavoprotein alpha polypeptide antibody
    • EMA antibody
    • ETFA antibody
    • ETFA_HUMAN antibody
    • GA2 antibody
    • Glutaric aciduria II antibody
    see all

Images

  • ab126131, at 1/100 dilution (green), staining methanol fixed HeLa cells by immunofluorescence.
  • ab126131, at 1/100 dilution, staining paraffin embedded Mouse C2C12 xenograft by immunohistochemistry.
  • ab126131, at 1/000 dilution, staining paraffin embedded Human colon carcinoma by immunohistochemistry.
  • All lanes : Anti-ETFA antibody (ab126131) at 1/1000 dilution

    Lane 1 : A431 whole cell lysate
    Lane 2 : HeLa whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 35 kDa

References

ab126131 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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