Anti-ETFDH antibody (ab103910)
Key features and details
- Goat polyclonal to ETFDH
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-ETFDH antibody
See all ETFDH primary antibodies -
Description
Goat polyclonal to ETFDH -
Host species
Goat -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Rabbit, Cow, Dog, Pig, Zebrafish, Orangutan -
Immunogen
Synthetic peptide:
C-EHDQPAHLTLRD
, corresponding to internal sequence amino acids 530-541 of Human ETFDH (NP_004444.2). -
Positive control
- Human, Mouse and Rat Heart lysates, Human kidney lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, Tris buffered saline -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
ab103910 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab103910 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB | (1) |
Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 69 kDa.
1 hour primary incubation is recommended for this product. |
Notes |
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WB
Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 69 kDa. 1 hour primary incubation is recommended for this product. |
Target
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Function
Accepts electrons from ETF and reduces ubiquinone. -
Involvement in disease
Defects in ETFDH are the cause of glutaric aciduria type 2C (GA2C) [MIM:231680]. GA2C is an autosomal recessively inherited disorder of fatty acid, amino acid, and choline metabolism. It is characterized by multiple acyl-CoA dehydrogenase deficiencies resulting in large excretion not only of glutaric acid, but also of lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. -
Sequence similarities
Belongs to the ETF-QO/fixC family.
Contains 1 4Fe-4S ferredoxin-type domain. -
Cellular localization
Mitochondrion inner membrane. - Information by UniProt
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Database links
- Entrez Gene: 768074 Cow
- Entrez Gene: 475480 Dog
- Entrez Gene: 2110 Human
- Entrez Gene: 100340346 Rabbit
- Omim: 231675 Human
- SwissProt: Q2KIG0 Cow
- SwissProt: Q16134 Human
- SwissProt: Q5RDD3 Orangutan
see all -
Alternative names
- Electron transfer flavoprotein ubiquinone oxidoreductase antibody
- Electron transfer flavoprotein-ubiquinone oxidoreductase antibody
- electron transferring flavoprotein dehydrogenase antibody
see all
Images
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Anti-ETFDH antibody (ab103910) at 1 µg/ml + Human Kidney lysate at 35 µg
Predicted band size: 69 kDa
Observed band size: 70 kDa why is the actual band size different from the predicted?
Datasheets and documents
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Datasheet download
References (0)
ab103910 has not yet been referenced specifically in any publications.