Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionAccepts electrons from ETF and reduces ubiquinone.
Involvement in diseaseDefects in ETFDH are the cause of glutaric aciduria type 2C (GA2C) [MIM:231680]. GA2C is an autosomal recessively inherited disorder of fatty acid, amino acid, and choline metabolism. It is characterized by multiple acyl-CoA dehydrogenase deficiencies resulting in large excretion not only of glutaric acid, but also of lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids.
Sequence similaritiesBelongs to the ETF-QO/fixC family. Contains 1 4Fe-4S ferredoxin-type domain.