AbcamBiochemicals

Ethacridine lactate monohydrate (ab143396)

Overview

  • Product nameEthacridine lactate monohydrate
  • Description
    DNA intercalating antiseptic agent
  • Biological descriptionDNA intercalating antiseptic agent. Activates uterine mast cells. Induces myometrial contractions (EC50 = 10 μM). Shows abortifacient effects in vivo.
  • Purity> 98%

Properties

  • Chemical name7-Ethoxyacridine-3,9-diamine lactate hydrate
  • Molecular Weight361.39
  • Chemical structureChemical Structure
  • Molecular formulaC15H15N3O.C3H6O3.H2O
  • CAS Number6402-23-9
  • PubChem identifier165457
  • Storage instructionsStore at room temperature.
  • Solubility overviewSoluble in water
  • Handling

    Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 12 months.

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILESCCOC1=CC2=C(C3=C(C=C(C=C3)N)N=C2C=C1)N.CC(C(=O)O)O.O
  • Source

    Synthetic

  • Research Areas

    References for Ethacridine lactate monohydrate (ab143396)

    This product has been referenced in:
    • Gan HT  et al. Characterization and removal of aggregates formed by nonspecific interaction of IgM monoclonal antibodies with chromatin catabolites during cell culture production. J Chromatogr A 1291:33-40 (2013). Read more (PubMed: 23598159) »
    • Rudolph MI  et al. On the mechanism of action of ethodin in inducing myometrium contractions. Gen Pharmacol 28:381-5 (1997). Read more (PubMed: 9068977) »
    • Rudolph MI  et al. Ethodin: pharmacological evidence of the interaction between smooth muscle and mast cells in the myometrium. J Pharmacol Exp Ther 282:256-61 (1997). Read more (PubMed: 9223562) »

    See 0 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"