Overview

  • Product nameAnti-EVA1 antibody
    See all EVA1 primary antibodies
  • Description
    Mouse polyclonal to EVA1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length EVA1 protein (Human)

  • Positive control
    • EVA1 transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab67581 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 26 kDa (predicted molecular weight: 24 kDa).

Target

  • RelevanceEpithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. EVA1 is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain; a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. EVA1 expression is elevated in some T-cell leukemias. There are two isoforms.
  • Cellular localizationCell Membrane; Single-pass type I membrane protein, cytoskeleton
  • Database links
  • Alternative names
    • Epithelial V like antigen 1 antibody
    • EVA antibody
    • EVA1 antibody
    • MPZL2 antibody
    • MPZL2 myelin protein zero like 2 antibody
    • Myelin protein zero like 2 antibody
    • Myelin protein zero like protein 2 antibody
    see all

Anti-EVA1 antibody images

  • All lanes : Anti-EVA1 antibody (ab67581) at 1/500 dilution

    Lane 1 : EVA1 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 24 kDa
    Observed band size : 26 kDa (why is the actual band size different from the predicted?)

References for Anti-EVA1 antibody (ab67581)

ab67581 has not yet been referenced specifically in any publications.

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