Overview

  • Product name
    Evans blue (mM/ml)
  • Description
    Potent inhibitor of L-glutamate uptake. 1 ml water soluble pack.
  • Biological description
    Potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT). Able to antagonize AMPA and kainate receptor mediated currents (IC50 values are 220 and 150 nM, respectively). Binds with high affinity to serum albumin.

    Soluble in 1 ml water to give specified mM/ml concentration. Find out more.
  • Purity
    > 95%

Properties

  • Chemical name
    6,6'-[(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(2,1-diazenediyl)]bis[4-amino-5-hydroxy-1,3-naphthalenedisulfonic acid] tetrasodium salt
  • Molecular weight
    960.80
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C34H24N6Na4O14S4
  • CAS Number
    314-13-6
  • PubChem identifier
    9566057
  • Storage instructions
    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in 1 ml water to give specified mM/ml concentration
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES
    O=S(=O)(O[Na])c6cc(c(N)c5c6ccc(/N=N/c1ccc(cc1C)c4ccc(/N=N/c3ccc2c(cc(c(N)c2c3O)S(=O)(=O)O[Na])S(=O)(=O)O[Na])c(C)c4)c5O)S(=O)(=O)O[Na]
  • Source

    Synthetic

  • Research areas

References

ab146727 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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