Overview

  • Product nameAnti-EVER2 antibody
    See all EVER2 primary antibodies
  • Description
    Rabbit polyclonal to EVER2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 143-192,

    PGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFTNTYLFYGAYRVG

    , of Human TMC8 (NP_689681).

  • Positive control
    • 721B cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab102583 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 82 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • RelevanceEpidermodysplasia verruciformis (EV) is an autosomal recessive genodermatosis associated with a high risk of skin cancers resulting from a high susceptibility to infection by specific human papillomaviruses. Mutations in two homologous genes EVER1 and EVER2 cause the majority of EV cases. These two proteins form a complex and interact with the zinc transporter ZnT-1 in the endoplasmic reticulum. Cells lacking EVER2 accumulated higher levels of zinc in the nucleolus and nucleus compare to those cells with and intact EVER2 gene, indicating that one role of EVER2 is to regulate the intracellular distribution of zinc. At least two isoforms of EVER2 are known to exist.
  • Cellular localizationEndoplasmic reticulum membrane; Multi pass membrane protein.
  • Database links
  • Alternative names
    • epidermodysplasia verruciformis 2 antibody
    • Epidermodysplasia verruciformis protein 2 antibody
    • EV2 antibody
    • EVIN2 antibody
    • FLJ40668 antibody
    • FLJ43684 antibody
    • MGC102701 antibody
    • MGC40121 antibody
    • TMC8 antibody
    • Transmembrane channel like protein 8 antibody
    see all

Anti-EVER2 antibody images

  • Anti-EVER2 antibody (ab102583) at 1 µg/ml + 721B cell lysate at 10 µg

    Predicted band size : 82 kDa

References for Anti-EVER2 antibody (ab102583)

ab102583 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your inquiry.

Unfortunately, we are not able to release the immunogen sequence for ab67325 and ab69859 as it is proprietary information.

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I have contacted the lab asking for the immunogen of ab67325 and ab69859 and will let you know when I get a reply back from them.

With regards to the additional band seen on the WB for ab102583, here is...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"