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Rabbit polyclonal to EXOC7
Predicted to work with:
Recombinant protein fragment containing a sequence corresponding to a region within amino acids 74 and 345 of EXOC7 (NP_001013861; UniProt ID: Q9UPT5 isoform 1).
WB: HeLa whole cell lysate; H1299, HepG2 and MOLT4 cell lysates
ICC/IF: A431 cell
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
Concentration information loading...
Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 78 kDa.
1/100 - 1/200.
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion.
Belongs to the EXO70 family.
The N-terminus is involved in SEC8 and ARHQ binding.
The C-terminus is required for translocation to the plasma membrane.
Cytoplasm > cytosol. Cell membrane. Translocates, as a preformed complex with SEC6 and SEC8, to the plasma membrane in response to insulin through the activation of ARHQ.
Information by UniProt
2 5 3p antibody
Western blot - Anti-EXOC7 antibody (ab95981)
Anti-EXOC7 antibody (ab95981) at 1/1000 dilution + HeLa whole cell lysate at 30 µg
Predicted band size: 78 kDa 7.5% SDS PAGE
Immunocytochemistry/ Immunofluorescence - Anti-EXOC7 antibody (ab95981)
Immunofluorescence analysis of paraformaldehyde-fixed A431, using ab95981 at 1/200 dilution. Lower image merged with DNA probe.
has not yet been referenced specifically in any publications.
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