Overview

  • Product name
  • Description
    Rabbit polyclonal to EXOSC3
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Cow
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 1-168 of Human EXOSC3 (AAH02437).

  • Positive control
    • A431, Jurkat and Raji whole cell lysates; 293T cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 20% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab104161 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 30 kDa.

Target

  • Relevance
    EXOSC3 is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions. It is required for the 3'processing of the 7S pre-RNA to the mature 5.8S rRNA. Has a 3'-5' exonuclease activity. [Swiss-Prot]
  • Cellular localization
    Cytoplasm. Nucleus, nucleolus.
  • Database links
  • Alternative names
    • bA3J10.7 antibody
    • CGI 102 antibody
    • CGI-102 antibody
    • Exosome complex component RRP40 antibody
    • Exosome complex exonuclease RRP40 antibody
    • Exosome component 3 antibody
    • hRrp 40 antibody
    • hRrp-40 antibody
    • hRrp40 antibody
    • hRrp40p antibody
    • p10 antibody
    • PCH1B antibody
    • Ribosomal RNA processing protein 40 antibody
    • Ribosomal RNA-processing protein 40, S. cerevisiae, homolog of antibody
    • RP11-3J10.8 antibody
    • RRP 40 antibody
    • Rrp40 antibody
    • Rrp40p antibody
    see all

Images

  • All lanes : Anti-EXOSC3 antibody (ab104161) at 1/1000 dilution

    Lane 1 : A431 whole cell lysate
    Lane 2 : Jurkat whole cell lysate
    Lane 3 : Raji whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 30 kDa

References

This product has been referenced in:
  • Haas G  et al. Identification of factors involved in target RNA-directed microRNA degradation. Nucleic Acids Res 44:2873-87 (2016). WB ; Human . Read more (PubMed: 26809675) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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