• Product name
  • Description
    Mouse polyclonal to EXOSC3
  • Host species
  • Tested applications
    Suitable for: WB, ELISA, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length human EXOSC3 protein (NP_057126.2).

  • Positive control
    • WB: Human pancreas tissue lysate; EXOSC3 transfected 293T cell lysate ICC/IF: HepG2 cell


  • Form
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: 1 x PBS, pH 7.2
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
  • Isotype
  • Research areas


Our Abpromise guarantee covers the use of ab88859 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 30 kDa (predicted molecular weight: 30 kDa).
ELISA Use at an assay dependent dilution.
ICC/IF Use a concentration of 10 µg/ml.


  • Relevance
    EXOSC3 is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions. It is required for the 3'processing of the 7S pre-RNA to the mature 5.8S rRNA. Has a 3'-5' exonuclease activity. [Swiss-Prot]
  • Cellular localization
    Cytoplasm. Nucleus, nucleolus.
  • Database links
  • Alternative names
    • bA3J10.7 antibody
    • CGI 102 antibody
    • CGI-102 antibody
    • Exosome complex component RRP40 antibody
    • Exosome complex exonuclease RRP40 antibody
    • Exosome component 3 antibody
    • hRrp 40 antibody
    • hRrp-40 antibody
    • hRrp40 antibody
    • hRrp40p antibody
    • p10 antibody
    • PCH1B antibody
    • Ribosomal RNA processing protein 40 antibody
    • Ribosomal RNA-processing protein 40, S. cerevisiae, homolog of antibody
    • RP11-3J10.8 antibody
    • RRP 40 antibody
    • Rrp40 antibody
    • Rrp40p antibody
    see all


  • Anti-EXOSC3 antibody (ab88859) at 1 µg/ml + human pancreas tissue lysate at 50 µg

    Predicted band size: 30 kDa
    Observed band size: 30 kDa

  • All lanes : Anti-EXOSC3 antibody (ab88859) at 1 µg/ml

    Lane 1 : lysate from EXOSC3 transfected 293T cells
    Lane 2 : lysate from non transfected 293T cells

    Lysates/proteins at 25 µg per lane.

    Predicted band size: 30 kDa
    Observed band size: 30 kDa

  • ab88859, at 10 µg/ml, staining EXOSC3 in paraformaldehyde fixed, permeabilized HepG2 cell by Immunofluorescence.


ab88859 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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We have 3 antibodies ab6035, ab6039 and ab82149 available from the same collaborator as for ab6038, and ab6036. It is hard to guess if these 3 antibodies will perform as good as ab6038/ ab6036 antibodies or even ...

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