Recombinant
RabMAb

Anti-EXTL2 antibody [EPR11130] (ab168391)

Overview

  • Product name
    Anti-EXTL2 antibody [EPR11130]
    See all EXTL2 primary antibodies
  • Description
    Rabbit monoclonal [EPR11130] to EXTL2
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
    Unsuitable for: ICC
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide, corresponding to residues in Human EXTL2 (UniProt: Q9UBQ6).

  • Positive control
    • Human fetal heart, mouse brain, mouse heart, mouse kidney, rat brain, rat heart and rat kidney lysates; Human colon tissue and thyroid carcinoma tissue.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab168391 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 37 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
  • Application notes
    Is unsuitable for ICC.
  • Target

    • Function
      Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.
    • Tissue specificity
      Ubiquitous.
    • Pathway
      Glycan metabolism; heparan sulfate biosynthesis.
    • Sequence similarities
      Belongs to the glycosyltransferase 47 family.
    • Post-translational
      modifications
      The soluble form derives from the membrane form by proteolytic processing.
    • Cellular localization
      Endoplasmic reticulum membrane and Secreted. A soluble form is found in the serum.
    • Information by UniProt
    • Database links
    • Alternative names
      • 4-N-acetylhexosaminyltransferase EXTL2 antibody
      • Alpha 1 4 N acetylhexosaminyltransferase EXTL2 antibody
      • Alpha GalNAcT EXTL2 antibody
      • Alpha-1 antibody
      • Alpha-GalNAcT EXTL2 antibody
      • Exostoses (multiple) like 2 antibody
      • Exostoses multiple like 2 antibody
      • Exostosin like 2 antibody
      • Exostosin like glycosyltransferase 2 antibody
      • EXT L2 antibody
      • EXT related protein 2 antibody
      • EXT-related protein 2 antibody
      • EXTL 2 antibody
      • EXTL2 antibody
      • EXTL2_HUMAN antibody
      • EXTR 2 antibody
      • EXTR2 antibody
      • Glucuronyl galactosyl proteoglycan 4 alpha N acetylglucosaminyltransferase antibody
      • Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase antibody
      • Multiple exostoses like 2 antibody
      • Processed exostosin like 2 antibody
      • Processed exostosin-like 2 antibody
      see all

    Images

    • All lanes : Anti-EXTL2 antibody [EPR11130] (ab168391) at 1/1000 dilution

      Lane 1 : Human fetal heart lysate
      Lane 2 : Mouse brain lysate
      Lane 3 : Mouse heart lysate
      Lane 4 : Mouse kidney lysate
      Lane 5 : Rat brain lysate
      Lane 6 : Rat heart lysate
      Lane 7 : Rat kidney lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size: 37 kDa

    • Immunohistochemical analysis of paraffin-embedded Human colon tissue labeling EXTL2 with ab168391 at 1/50 dilution.
    • Immunohistochemical analysis of paraffin-embedded Human thyroid carcinoma tissue labeling EXTL2 with ab168391 at 1/50 dilution.

    References

    ab168391 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab168391.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up