Overview

  • Product nameAnti-EYS antibody
  • Description
    Mouse monoclonal to EYS
  • Tested applicationsSuitable for: WB, ELISA, Sandwich ELISAmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 309-408 of Human EYS with a proprietary tag (XP_498111).

  • Positive control
    • Recombinant Human EYS Protein.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferpH: 7.20
    Constituent: 99% PBS
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityMonoclonal
  • IsotypeIgG2a
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab118104 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 351 kDa. XP_498111
ELISA Use at an assay dependent dilution.
Sandwich ELISA Use a concentration of 10 µg/ml.

Target

  • FunctionRequired to maintain the integrity of photoreceptor cells.
  • Tissue specificityPresent in retina.
  • Involvement in diseaseDefects in EYS are the cause of retinitis pigmentosa type 25 (RP25) [MIM:602772]. RP leads to degeneration of retinal photoreceptor cells. Patients suffer from night blindness, beginning at approximately 25 years of age, and deterioration of visual acuity (central vision), beginning at approximately 30 years of age. By age 55 to 60 years, many affected subjects have no perception of light in either eye.
  • Sequence similaritiesBelongs to the EYS family.
    Contains 27 EGF-like domains.
    Contains 5 laminin G-like domains.
  • Cellular localizationSecreted. Localizes in the photoreceptor cell layer.
  • Information by UniProt
  • Database links
  • Alternative names
    • bA166P24.2 antibody
    • bA307F22.3 antibody
    • bA74E24.1 antibody
    • C6orf178 antibody
    • C6orf179 antibody
    • C6orf180 antibody
    • dJ1018A4.2 antibody
    • dJ22I17.2 antibody
    • dJ303F19.1 antibody
    • EGF-like protein 10 antibody
    • EGF-like protein 11 antibody
    • EGF-like-domain, multiple 10 antibody
    • EGF-like-domain, multiple 11 antibody
    • EGFL10 antibody
    • EGFL11 antibody
    • Epidermal growth factor-like protein 10 antibody
    • Epidermal growth factor-like protein 11 antibody
    • Eyes shut homolog (Drosophila) antibody
    • EYS antibody
    • EYS_HUMAN antibody
    • KIAA0663 antibody
    • OTTHUMP00000016688 antibody
    • OTTHUMP00000179129 antibody
    • OTTHUMP00000213100 antibody
    • OTTHUMP00000217891 antibody
    • Protein eyes shut homolog antibody
    • Protein spacemaker homolog antibody
    • RP25 antibody
    • SPAM antibody
    see all

Anti-EYS antibody images

  • Anti-EYS antibody (ab118104) at 5 µg/ml + recombinant immunogen at 0.2 µg
    Developed using the ECL technique

    Predicted band size : 351 kDa
  • ab118104 at 10 µg/ml as a capture antibody. The detection limit for recombinant tagged EYS is 0.3 ng/ml.

References for Anti-EYS antibody (ab118104)

ab118104 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"