Overview

  • Product name
  • Description
    Goat polyclonal to FAAH1
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Dog
  • Immunogen

    Synthetic peptide conjugated to KLH, from C-terminal of Human FAAH1.

  • Positive control
    • Human Brain cortex and Human testis tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab110840 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates.
  • Tissue specificity
    Highly expressed in the brain, small intestine, pancreas, skeletal muscle and testis. Also expressed in the kidney, liver, lung, placenta and prostate.
  • Sequence similarities
    Belongs to the amidase family.
  • Cellular localization
    Endomembrane system. Cytoplasm > cytoskeleton. Seems to be attached to intracellular membranes and a portion of the cytoskeletal network.
  • Information by UniProt
  • Database links
  • Alternative names
    • Anandamide amidohydrolase 1 antibody
    • Anandamide amidohydrolase antibody
    • FA2H antibody
    • FAAH antibody
    • FAAH-1 antibody
    • FAAH1_HUMAN antibody
    • Fatty acid 2-hydroxylase antibody
    • Fatty acid alpha-hydroxylase antibody
    • Fatty acid amide hydrolase antibody
    • Fatty-acid amide hydrolase 1 antibody
    • MGC102823 antibody
    • MGC138146 antibody
    • Oleamide hydrolase 1 antibody
    • Oleamide hydrolase antibody
    see all

Images

  • ab110840 at 3.75 µg/ml staining FAAH1 in formalin-fixed, paraffin-embedded Human Brain cortex tissue by Immunohistochemistry.
  • ab110840 at 3.75 µg/ml staining FAAH1 in formalin-fixed, paraffin-embedded Human Testis tissue by Immunohistochemistry.

References

ab110840 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Application
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Blocking step
Serum as blocking agent for 45 minute(s) · Concentration: 2.5% · Temperature: RT°C
Antigen retrieval step
Heat mediated - Buffer/Enzyme Used: Tris EDTA ph 9
Sample
Dog Tissue sections (Canis familiaris hippocampus)
Specification
Canis familiaris hippocampus
Permeabilization
No
Fixative
Formaldehyde
Username

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Verified customer

Submitted Oct 24 2014

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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