Overview

  • Product nameAnti-Factor D antibody
    See all Factor D primary antibodies
  • Description
    Rabbit polyclonal to Factor D
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Guinea pig, Cow, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 160-209 (GRRPDSLQHV LLPVLDRATC NRRTHHDGAI TERLMCAESN RRDSCKGDSG) of Human Factor D (NP_001919).

  • Positive control
    • Human Fetal Lung lysate.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferConstituents: 98% PBS, 2% Sucrose
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab111880 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.2 - 1 µg/ml. Predicted molecular weight: 27 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionFactor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
  • Involvement in diseaseDefects in CFD are the cause of complement factor D deficiency (CFD deficiency) [MIM:134350]. CFD deficiency predisposes to invasive meningococcal disease.
  • Sequence similaritiesBelongs to the peptidase S1 family.
    Contains 1 peptidase S1 domain.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Adipsin antibody
    • Adipsin/complement factor D antibody
    • Adn antibody
    • C3 convertase activator antibody
    • CFAD_HUMAN antibody
    • CFD antibody
    • Complement factor D antibody
    • complement factor D preproprotein antibody
    • D component of complement antibody
    • DF antibody
    • FactorD antibody
    • PFD antibody
    • Properdin factor D antibody
    see all

Anti-Factor D antibody images

  • Anti-Factor D antibody (ab111880) at 1 µg/ml + Human Fetal Lung Lysate at 10 µg

    Predicted band size : 27 kDa

References for Anti-Factor D antibody (ab111880)

ab111880 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"