• Product nameAnti-Factor I antibody
    See all Factor I primary antibodies
  • Description
    Rabbit polyclonal to Factor I
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from an internal domain of human Factor I.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: Whole serum
  • PurityWhole antiserum
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab82703 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/500.
WB 1/200 - 1/2000. Predicted molecular weight: 65 kDa.


  • FunctionResponsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively.
  • Tissue specificityPlasma.
  • Involvement in diseaseDefects in CFI are a cause of susceptibility to hemolytic uremic syndrome atypical type 3 (AHUS3) [MIM:612923]. An atypical form of hemolytic uremic syndrome. It is a complex genetic disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, renal failure and absence of episodes of enterocolitis and diarrhea. In contrast to typical hemolytic uremic syndrome, atypical forms have a poorer prognosis, with higher death rates and frequent progression to end-stage renal disease. Note=Susceptibility to the development of atypical hemolytic uremic syndrome can be conferred by mutations in various components of or regulatory factors in the complement cascade system. Other genes may play a role in modifying the phenotype.
    Defects in CFI are the cause of complement factor I deficiency (CFI deficiency) [MIM:610984]. CFI deficiency is an autosomal recessive condition associated with a propensity to pyogenic infections.
  • Sequence similaritiesBelongs to the peptidase S1 family.
    Contains 1 Kazal-like domain.
    Contains 2 LDL-receptor class A domains.
    Contains 1 peptidase S1 domain.
    Contains 1 SRCR domain.
  • Cellular localizationSecreted > extracellular space.
  • Information by UniProt
  • Database links
  • Alternative names
    • AHUS3 antibody
    • ARMD13 antibody
    • C3b INA antibody
    • C3b inactivator antibody
    • C3B/C4B inactivator antibody
    • C3BINA antibody
    • CFAI_HUMAN antibody
    • Cfi antibody
    • Complement component I antibody
    • Complement control protein factor I antibody
    • Complement factor I antibody
    • Complement factor I heavy chain antibody
    • Complement factor I light chain antibody
    • F1 antibody
    • factor I antibody
    • FactorI antibody
    • FI antibody
    • I factor antibody
    • IF antibody
    • KAF antibody
    • Konglutinogen activating factor antibody
    • Light chain of factor I antibody
    • OTTHUMP00000219728 antibody
    • OTTHUMP00000221928 antibody
    see all

References for Anti-Factor I antibody (ab82703)

ab82703 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab82703.
Please use the links above to contact us or submit feedback about this product.