Anti-Factor V Light Chain antibody [CBC-MOR101] (ab1009)


  • Product nameAnti-Factor V Light Chain antibody [CBC-MOR101]
    See all Factor V Light Chain primary antibodies
  • Description
    Mouse monoclonal [CBC-MOR101] to Factor V Light Chain
  • SpecificityThis antibody reacts with the light chain (mw ~74,000) of human Factor V.
  • Tested applicationsSuitable for: ELISA, IHC-P, IHC-Fr, Neutralisingmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Purified human Factor V.

  • EpitopeThis antibody recognizes an epitope (exact sequence unknown) in the F1F2 polypeptide of human Factor V and activated Factor V (Factor Va).


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPBS, pH7.2
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • Clone numberCBC-MOR101
  • IsotypeIgG1
  • Research areas


Our Abpromise guarantee covers the use of ab1009 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesThis antibody neutralizes Factor V activity. KD = 0.3 x 10-10mol/L.
    This antibody can also be used for autoradiography.
  • Target

    • RelevanceCoagulation factor V is a cofactor that participates with factor Xa to activate prothrombin to thrombin. Factor Va is composed of a heavy chain and a light chain, noncovalently bound. The interaction between the two chains is calcium-dependent. Thrombin activates factor V proteolytically to the active cofactor, factor Va (formation of a heavy chain at the N-terminus and a light chain at the C-terminus). Sulfation is required for efficient thrombin cleavage and activation and for full procoagulant activity. Defects in F5 are the cause of Owren parahemophilia which is an hemorrhagic diastesis. Defects in F5 are the cause of resistance to activated protein C (APCR). APCR is a form of thrombophilia. The APCR mutation is found in about 5% of the population which suggest that a slight thrombotic tendency may confer some advantage in fetal implantation.
    • Cellular localizationSecreted
    • Database links
    • Alternative names
      • Activated protein C cofactor antibody
      • Coagulation factor V antibody
      • Coagulation factor V heavy chain antibody
      • Coagulation factor V light chain antibody
      • F5 antibody
      see all

    References for Anti-Factor V Light Chain antibody [CBC-MOR101] (ab1009)

    This product has been referenced in:

    See 1 Publication for this product

    Product Wall

    Thank you for your enquiry. These antibodies are two different clones. Ab1009 - Mouse monoclonal [CBC-MOR101] to Factor V Light Chain - recognizes an epitope (exact sequence unknown) in the F1F2 polypeptide of human Factor V and actiVated Factor V (Fac...

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    Thank you for your enquiry. For ab21037, the antibody was tested against purified Human Factor V and against human plasma in ELISA and Western blot. The characterization of ab20951, MAb to Factor V (Clone 701), was described in the following publish...

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    Anti-Factor V staining is seen in the cytoplasm of platelets and megakaryo-cytes.

    Human bone marrow smears can be used. Marrows are smeared, air-dried, fixed immediately in methanol:acetone (1:9) and stored frozen at -20 C until used.