Overview

  • Product name
    Anti-Factor X antibody (Biotin)
    See all Factor X primary antibodies
  • Description
    Rabbit polyclonal to Factor X (Biotin)
  • Conjugation
    Biotin
  • Tested applications
    Suitable for: WB, RIAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Human Factor X purified from human plasma

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 50% Glycerol, PBS, pH 7.5
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab79926 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
RIA
  • Application notes
    EIA/RIA: Use at a concentration of 3 µg/ml.
    WB: Use at an assay dependent dilution. Predicted molecular weight: 55 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.
    • Tissue specificity
      Plasma; synthesized in the liver.
    • Involvement in disease
      Defects in F10 are the cause of factor X deficiency (FA10D) [MIM:227600]. A hemorrhagic disease with variable presentation. Affected individuals can manifest prolonged nasal and mucosal hemorrhage, menorrhagia, hematuria, and occasionally hemarthrosis. Some patients do not have clinical bleeding diathesis.
    • Sequence similarities
      Belongs to the peptidase S1 family.
      Contains 2 EGF-like domains.
      Contains 1 Gla (gamma-carboxy-glutamate) domain.
      Contains 1 peptidase S1 domain.
    • Post-translational
      modifications
      The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium.
      N- and O-glycosylated.
      The activation peptide is cleaved by factor IXa (in the intrinsic pathway), or by factor VIIa (in the extrinsic pathway).
      The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.
    • Cellular localization
      Secreted.
    • Information by UniProt
    • Database links
    • Form
      Cleaved into the following 3 chains: 1. Factor X light chain 2. Factor X heavy chain 3. Activated factor Xa heavy chain
    • Alternative names
      • Activated factor Xa heavy chain antibody
      • Coagulation factor X antibody
      • F10 antibody
      • FA10_HUMAN antibody
      • factor Xa antibody
      • FX antibody
      • FXA antibody
      • Prothrombinase antibody
      • Stuart factor antibody
      • Stuart Prower factor antibody
      • Stuart-Prower factor antibody
      see all

    References

    ab79926 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab79926.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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