• Product nameAnti-FADD antibody
    See all FADD primary antibodies
  • Description
    Rabbit polyclonal to FADD
  • Specificityab55399 detects endogenous levels of total FADD protein.
  • Tested applicationsSuitable for: WB, IHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic non-phosphopeptide derived from human FADD around the phosphorylation site of serine 194 (A-M-S-P-M).

  • Positive control
    • Human lung carcinoma tissue and HeLa cell extract, treated with PMA(125ng/ml, 30mins).



Our Abpromise guarantee covers the use of ab55399 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 30 kDa (predicted molecular weight: 23 kDa).
IHC-P Use at an assay dependent concentration.
ELISA 1/5000.


  • FunctionApoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
  • Tissue specificityExpressed in a wide variety of tissues, except for peripheral blood mononuclear leukocytes.
  • Sequence similaritiesContains 1 death domain.
    Contains 1 DED (death effector) domain.
  • DomainContains a death domain involved in the binding of the corresponding domain within Fas receptor.
  • Information by UniProt
  • Database links
  • Alternative names
    • FADD antibody
    • FADD protein antibody
    • FADD_HUMAN antibody
    • Fas (TNFRSF6) associated via death domain antibody
    • Fas associated via death domain antibody
    • Fas associating death domain containing protein antibody
    • Fas associating protein antibody
    • Fas associating protein with death domain antibody
    • Fas TNFRSF6 associated via death domain antibody
    • FAS-associated death domain protein antibody
    • FAS-associating death domain-containing protein antibody
    • GIG 3 antibody
    • GIG3 antibody
    • Growth inhibiting gene 3 protein antibody
    • Growth-inhibiting gene 3 protein antibody
    • H sapiens mRNA for mediator of receptor induced toxicity antibody
    • Mediator of receptor induced toxicity antibody
    • MGC8528 antibody
    • MORT 1 antibody
    • MORT1 antibody
    • Protein FADD antibody
    see all

Anti-FADD antibody images

  • Immunohistochemical analysis of paraffin embedded human lung carcinoma tissue using ab55399 (1/50 dilution) in the presence and absence of immunizing peptide.
  • All lanes : Anti-FADD antibody (ab55399) at 1/500 dilution

    Lane 1 : HeLa cell extract, treated with PMA (125ng/ml, 30mins), without immunizing peptide
    Lane 2 : HeLa cell extract, treated with PMA (125ng/ml, 30mins), with immunizing peptide

    Predicted band size : 23 kDa
    Observed band size : 30 kDa (why is the actual band size different from the predicted?)

References for Anti-FADD antibody (ab55399)

ab55399 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab55399.
Please use the links above to contact us or submit feedback about this product.