Overview

  • Product nameAnti-FADS1 antibody [2D9]
    See all FADS1 primary antibodies
  • Description
    Mouse monoclonal [2D9] to FADS1
  • Tested applicationsSuitable for: WB, IHC-P, Sandwich ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within N terminal amino acids 1-100 of Human FADS1 with a 26kDa proprietary tag (NP_037534).

  • Positive control
    • Human testis tissue; HeLa cell line nuclear extract.

Properties

Applications

Our Abpromise guarantee covers the use of ab124363 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 52 kDa.
IHC-P Use a concentration of 5 µg/ml.
Sandwich ELISA Use at an assay dependent concentration.

Target

  • FunctionComponent of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the desaturation of dihomo-gamma-linoleic acid (DHGLA) (20:3n-6) and eicosatetraenoic acid (20:4n-3) to generate arachidonic acid (AA) (20:4n-6) and eicosapentaenoic acid (EPA)(20:5n-3) respectively.
  • Tissue specificityExpressed in many tissues, it is most abundant in the liver, brain, adrenal gland and heart. Found as well in skeletal muscle, lung, placenta, kidney, pancreas and retina.
  • PathwayLipid metabolism; polyunsaturated fatty acid biosynthesis.
  • Sequence similaritiesBelongs to the fatty acid desaturase family.
    Contains 1 cytochrome b5 heme-binding domain.
  • Developmental stageHighly expressed in fetal liver and fetal brain.
  • DomainThe histidine box domains may contain the active site and/or be involved in metal ion binding.
  • Cellular localizationEndoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • D5D antibody
    • Delta 5 desaturase antibody
    • Delta 5 fatty acid desaturase antibody
    • Delta(5) desaturase antibody
    • Delta(5) fatty acid desaturase antibody
    • Delta-5 desaturase antibody
    • Fads1 antibody
    • FADS1_HUMAN antibody
    • FADS6 antibody
    • FADSD5 antibody
    • Fatty acid desaturase 1 antibody
    • FLJ38956 antibody
    • Linoleoyl CoA desaturase (delta 6 desaturase) like 1 antibody
    • LLCDL1 antibody
    • TU12 antibody
    see all

Anti-FADS1 antibody [2D9] images

  • Anti-FADS1 antibody [2D9] (ab124363) at 1/500 dilution + HeLa cell line nuclear lysate

    Predicted band size : 52 kDa
  • ab124363, at 5 µg/ml, staining FADS1 in formalin-fixed, paraffin-embedded Human testis tissue by Immunohistochemistry.
  • Detection limit for recombinant proprietary tagged FADS1 is approximately 0.03ng/ml with ab124363 as a capture antibody.

References for Anti-FADS1 antibody [2D9] (ab124363)

ab124363 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"