For the best experience on the Abcam website please upgrade to a modern browser such as
Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer pH: 7.20 Constituent: 99% PBS
Concentration information loading...
Clone number 2D9
Light chain type kappa
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Predicted molecular weight: 52 kDa.
Use a concentration of 5 µg/ml.
Use at an assay dependent concentration.
Function Component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the desaturation of dihomo-gamma-linoleic acid (DHGLA) (20:3n-6) and eicosatetraenoic acid (20:4n-3) to generate arachidonic acid (AA) (20:4n-6) and eicosapentaenoic acid (EPA)(20:5n-3) respectively.
Tissue specificity Expressed in many tissues, it is most abundant in the liver, brain, adrenal gland and heart. Found as well in skeletal muscle, lung, placenta, kidney, pancreas and retina.
Pathway Lipid metabolism; polyunsaturated fatty acid biosynthesis.
Sequence similarities Belongs to the fatty acid desaturase family. Contains 1 cytochrome b5 heme-binding domain.
Developmental stage Highly expressed in fetal liver and fetal brain.
Domain The histidine box domains may contain the active site and/or be involved in metal ion binding.
Cellular localization Endoplasmic reticulum membrane.
Information by UniProt
Delta 5 desaturase antibody
Delta 5 fatty acid desaturase antibody
Anti-FADS1 antibody [2D9] images
Western blot - Anti-FADS1 antibody [2D9] (ab124363)
Anti-FADS1 antibody [2D9] (ab124363) at 1/500 dilution + HeLa cell line nuclear lysate Predicted band size : 52 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FADS1 antibody [2D9] (ab124363)
ab124363, at 5 µg/ml, staining FADS1 in formalin-fixed, paraffin-embedded Human testis tissue by Immunohistochemistry.
Sandwich ELISA - Anti-FADS1 antibody [2D9] (ab124363)
Detection limit for recombinant proprietary tagged FADS1 is approximately 0.03ng/ml with ab124363 as a capture antibody.
References for Anti-FADS1 antibody [2D9] (ab124363)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"