Overview

  • Product name
  • Description
    Goat polyclonal to FADS1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Dog, Baboon
  • Immunogen

    Synthetic peptide:

    C-QPSFEPTKNKELTDE

    , corresponding to internal sequence amino acids 97-111 of Human FADS1

  • Positive control
    • Human Lung lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab59031 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notes
    Peptide ELISA: antibody detection limit dilution 1:128,000.

    WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 52 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the desaturation of dihomo-gamma-linoleic acid (DHGLA) (20:3n-6) and eicosatetraenoic acid (20:4n-3) to generate arachidonic acid (AA) (20:4n-6) and eicosapentaenoic acid (EPA)(20:5n-3) respectively.
    • Tissue specificity
      Expressed in many tissues, it is most abundant in the liver, brain, adrenal gland and heart. Found as well in skeletal muscle, lung, placenta, kidney, pancreas and retina.
    • Pathway
      Lipid metabolism; polyunsaturated fatty acid biosynthesis.
    • Sequence similarities
      Belongs to the fatty acid desaturase family.
      Contains 1 cytochrome b5 heme-binding domain.
    • Developmental stage
      Highly expressed in fetal liver and fetal brain.
    • Domain
      The histidine box domains may contain the active site and/or be involved in metal ion binding.
    • Cellular localization
      Endoplasmic reticulum membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • D5D antibody
      • Delta 5 desaturase antibody
      • Delta 5 fatty acid desaturase antibody
      • Delta(5) desaturase antibody
      • Delta(5) fatty acid desaturase antibody
      • Delta-5 desaturase antibody
      • Fads1 antibody
      • FADS1_HUMAN antibody
      • FADS6 antibody
      • FADSD5 antibody
      • Fatty acid desaturase 1 antibody
      • FLJ38956 antibody
      • Linoleoyl CoA desaturase (delta 6 desaturase) like 1 antibody
      • LLCDL1 antibody
      • TU12 antibody
      see all

    Images

    References

    ab59031 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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