Overview

  • Product name
  • Description
    Goat polyclonal to FADS1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Dog, Baboon
  • Immunogen

    Synthetic peptide:

    C-QPSFEPTKNKELTDE

    , corresponding to internal sequence amino acids 97-111 of Human FADS1

  • Positive control
    • Human Lung lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab59031 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notes
    Peptide ELISA: antibody detection limit dilution 1:128,000.

    WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 52 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the desaturation of dihomo-gamma-linoleic acid (DHGLA) (20:3n-6) and eicosatetraenoic acid (20:4n-3) to generate arachidonic acid (AA) (20:4n-6) and eicosapentaenoic acid (EPA)(20:5n-3) respectively.
    • Tissue specificity
      Expressed in many tissues, it is most abundant in the liver, brain, adrenal gland and heart. Found as well in skeletal muscle, lung, placenta, kidney, pancreas and retina.
    • Pathway
      Lipid metabolism; polyunsaturated fatty acid biosynthesis.
    • Sequence similarities
      Belongs to the fatty acid desaturase family.
      Contains 1 cytochrome b5 heme-binding domain.
    • Developmental stage
      Highly expressed in fetal liver and fetal brain.
    • Domain
      The histidine box domains may contain the active site and/or be involved in metal ion binding.
    • Cellular localization
      Endoplasmic reticulum membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • D5D antibody
      • Delta 5 desaturase antibody
      • Delta 5 fatty acid desaturase antibody
      • Delta(5) desaturase antibody
      • Delta(5) fatty acid desaturase antibody
      • Delta-5 desaturase antibody
      • Fads1 antibody
      • FADS1_HUMAN antibody
      • FADS6 antibody
      • FADSD5 antibody
      • Fatty acid desaturase 1 antibody
      • FLJ38956 antibody
      • Linoleoyl CoA desaturase (delta 6 desaturase) like 1 antibody
      • LLCDL1 antibody
      • TU12 antibody
      see all

    Anti-FADS1 antibody images

    References for Anti-FADS1 antibody (ab59031)

    ab59031 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab59031.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up