Overview

  • Product nameAnti-FAM120A antibody
    See all FAM120A primary antibodies
  • Description
    Rabbit polyclonal to FAM120A
  • Specificityab106454 will not cross-react with FAM120B / PGCC1.
  • Tested applicationsSuitable for: ICC/IF, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    An 18 amino acid synthetic peptide from near the center of Human FAM120A (NP_055427).

  • Positive control
    • SK-N-SH cell lysate; Rat brain tissue.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab106454 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 122 kDa.
IHC-P Use at an assay dependent concentration.

Target

  • FunctionMay participate in mRNA transport in the cytoplasm (By similarity). Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.
  • Tissue specificityUbiquitously expressed. Highly expressed in scirrhous-type gastric cancer tissues compared with normal gastric mucosa (at protein level).
  • Sequence similaritiesBelongs to the constitutive coactivator of PPAR-gamma family.
  • Post-translational
    modifications
    Arg-982 is dimethylated, probably to asymmetric dimethylarginine.
    Phosphorylated on tyrosine by src family kinases upon ultraviolet exposure.
  • Cellular localizationCytoplasm. Cell membrane. Translocates to plasma membrane upon ultraviolet exposure.
  • Information by UniProt
  • Database links
  • Alternative names
    • C9orf10 antibody
    • Chromosome 9 open reading frame 10 antibody
    • Constitutive coactivator of PPAR gamma like protein 1 antibody
    • Constitutive coactivator of PPAR-gamma-like protein 1 antibody
    • DNA polymerase transactivated protein 5 antibody
    • DNA polymerase transactivated protein 1 antibody
    • DNAPTP1 antibody
    • DNAPTP5 antibody
    • F120A_HUMAN antibody
    • FAM120A antibody
    • Family with sequence similarity 120A antibody
    • Hypothetical protein LOC23196 antibody
    • KIAA0183 antibody
    • LOC23196 antibody
    • MGC111527 antibody
    • MGC133257 antibody
    • OSSA antibody
    • Oxidative stress-associated Src activator antibody
    • Protein FAM120A antibody
    see all

Anti-FAM120A antibody images

  • Lane 1 : Anti-FAM120A antibody (ab106454) at 0.5 µg/ml
    Lane 2 : Anti-FAM120A antibody (ab106454) at 1 µg/ml

    Lane 1 : SK-N-SH cell lysate
    Lane 2 : SK-N-SH cell lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 122 kDa
  • ab106454, at 2.5µg/ml, staining FAM120A in Rat brain tissue by Immunohistochemistry.
  • Immunofluorescence of FAM120A in Rat Brain cells using ab106454 at 20 ug/ml.

References for Anti-FAM120A antibody (ab106454)

ab106454 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab106454.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"