Overview

  • Product nameAnti-FAM161A antibody
    See all FAM161A primary antibodies
  • Description
    Rabbit polyclonal to FAM161A
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 120-169 (RKEWVPTITV PEPFQMMIRE QKKKEESMKS KSDIEMVHKA LKKQEEDPEY) of Human FAM161A, isoform 2.

  • Positive control
    • Jurkat cell lysate.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage bufferConstituents: 98% PBS, 2% Sucrose
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG

Associated products

Applications

Our Abpromise guarantee covers the use of ab115810 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 65 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Tissue specificityIsoform 1 and isoform 3 are widely expressed with highest levels in retina and testis, with isoform 1 being the mot abundant in all tissues tested.
  • Involvement in diseaseDefects in FAM161A are the cause of retinitis pigmentosa type 28 (RP28) [MIM:606068]. A retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
  • Sequence similaritiesBelongs to the FAM161 family.
  • Information by UniProt
  • Database links
  • Alternative names
    • F161A_HUMAN antibody
    • Fam161a antibody
    • Family with sequence similarity 161, member A antibody
    • FLJ13305 antibody
    • Hypothetical protein LOC84140 antibody
    • MGC129982 antibody
    • MGC129983 antibody
    • OTTHUMP00000201353 antibody
    • Protein FAM161A antibody
    see all

Anti-FAM161A antibody images

  • Anti-FAM161A antibody (ab115810) at 1 µg/ml + Jurkat cell lysate at 10 µg

    Predicted band size : 65 kDa

References for Anti-FAM161A antibody (ab115810)

This product has been referenced in:
  • Karlstetter M  et al. Disruption of the retinitis pigmentosa 28 gene Fam161a in mice affects photoreceptor ciliary structure and leads to progressive retinal degeneration. Hum Mol Genet N/A:N/A (2014). WB ; Mouse . Read more (PubMed: 24833722) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"