• Product name
  • Description
    Rabbit polyclonal to FAM20C
  • Tested applications
    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    KLH conjugated synthetic peptide between amino acids 443-471 from the C terminal region of Human FAM20C (NP_064608.2).

  • Positive control
    • HepG2 cell lysate; Human breast carcinoma tissue This antibody gave a positive result when used in the following formaldehyde fixed cell lines: DU145



Our Abpromise guarantee covers the use of ab107079 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 64 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 10 µg/ml.


  • Function
    Calcium-binding protein which may play a role in dentin mineralization.
  • Tissue specificity
    Widely expressed.
  • Involvement in disease
    Defects in FAM20C are the cause of Raine syndrome (RNS) [MIM:259775]. RNS is an autosomal recessive osteosclerotic bone dysplasia with neonatal lethal outcome. Clinical features include generalized osteosclerosis, craniofacial dysplasia and microcephaly.
  • Sequence similarities
    Belongs to the FAM20 family.
  • Cellular localization
  • Information by UniProt
  • Database links
  • Alternative names
    • C76981 antibody
    • Dentin matrix protein 4 antibody
    • DKFZp547C074 antibody
    • DMP-4 antibody
    • DMP4 antibody
    • DMP4_HUMAN antibody
    • Extracellular serine/threonine protein kinase Fam20C antibody
    • Fam20c antibody
    • Family with sequence similarity 20 member C antibody
    • GEF CK antibody
    • Golgi enriched fraction casein kinase antibody
    • Protein FAM20C antibody
    • RNS antibody
    see all


  • ICC/IF image of ab107079 stained DU145 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab107079 at 10µg/ml overnight at +4°C. The secondary antibody (green) was DyLight® 488 goat anti- rabbit (ab96899) IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

  • Anti-FAM20C antibody (ab107079) at 1/100 dilution + HepG2 cell lysate at 35 µg

    Predicted band size : 64 kDa
  • ab107079, at a 1/50 dilution, staining FAM20C in formalin fixed, paraffin embedded Human breast carcinoma by Immunohistochemistry, followed by peroxidase conjugation of the secondary antibody and DAB staining.


ab107079 has not yet been referenced specifically in any publications.

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