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Rabbit polyclonal to FAM38B
Specific to isoforms 1, 2, 3 and 4.
Predicted to work with:
Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog
Synthetic peptide: AGNSTESSKT PVTIEKIYPY YVKAPSDSNS KPIKQLLSEN NFMDITIILS, corresponding to amino acids 2503-2552 of Human FAM38B
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Constituents: 2% Sucrose, PBS
Concentration information loading...
Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 318 kDa.
Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
Use at an assay dependent concentration.
Titre using peptide based assay: 1/312500.
Component of a mechanosensitive channel required for rapidly adapting mechanically activated (MA) currents. Required for Merkel-cell mechanotransduction. Plays a major role in light-touch mechanosensation.
Involvement in disease
Arthrogryposis, distal, 5
Arthrogryposis, distal, 3 Marden-Walker syndrome
Belongs to the PIEZO (TC 1.A.75) family.
Information by UniProt
Family with sequence similarity 38 member B antibody
Western blot - FAM38B antibody (ab81327)
Anti-FAM38B antibody (ab81327) at 1 µg/ml (in 5% skim milk / PBS buffer) + 721_B cell lysate at 10 µg
HRP conjugated anti Rabbit IgG at 1/50000 dilution
Predicted band size:
Observed band size:
95 kDa (
why is the actual band size different from the predicted?
Additional bands at:
70 kDa. We are unsure as to the identity of these extra bands.
Isoform 3 has predicted MW 81 kDa.
Gel concentration: 12%
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"