Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab66965 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 30 kDa (predicted molecular weight: 26 kDa).

Target

  • FunctionInduces apoptosis of alpha and beta cells in a dose- and time-dependent manner. Present in insulin secretory granules and likely cosecreted with insulin.
  • Tissue specificityHighly expressed in the pancreas. Also found in the colon, kidney, prostate, small intestine and testis.
  • Sequence similaritiesBelongs to the FAM3 family.
  • Post-translational
    modifications
    2 N-termini have been observed in the mature protein: the first at Glu-30, resulting from signal peptide cleavage, the second at Ser-46.
  • Cellular localizationSecreted. Localized in discrete vesicular and perinuclear structure.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2-21 antibody
    • C21orf11 antibody
    • C21orf76 antibody
    • Cytokine like protein 2 21 antibody
    • Cytokine-like protein 2-21 antibody
    • Fam3b antibody
    • FAM3B_HUMAN antibody
    • Family with sequence similarity 3 member B antibody
    • ORF9 antibody
    • Pancreatic-derived factor antibody
    • PANDER antibody
    • PRED44 antibody
    • Protein FAM3B antibody
    see all

Anti-FAM3B antibody images

  • All lanes : Anti-FAM3B antibody (ab66965) at 1/500 dilution

    Lane 1 : Transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    Lane 1 : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution
    Lane 2 : Goat Anti Mouse IgG (H&L) HRP Conjugate at 1/5000 dilution


    Predicted band size : 26 kDa
    Observed band size : 30 kDa (why is the actual band size different from the predicted?)

References for Anti-FAM3B antibody (ab66965)

ab66965 has not yet been referenced specifically in any publications.

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