Overview

  • Product name
  • Description
    Rabbit polyclonal to FAM83H
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Rat, Human
  • Immunogen

    antigen sequence: SDKDKCSAIF RSDSLGTQGR LSRTLPASAE ERDRLLRRME SMRKEKRVYS RFEVFCKKEE ASSPGAGEGP AEEGTRDSKV GKFVPKILGT F, corresponding to amino acids 1085-1175 of Human FAM83H.

  • Positive control
    • Human vagina tissue; RT-4 lysate and Human tonsil lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab121816 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/10 - 1/20. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.

Target

  • Function
    May play a major role in the structural organization and calcification of developing enamel.
  • Tissue specificity
    Expressed in the tooth follicle.
  • Involvement in disease
    Defects in FAM83H are the cause of amelogenesis imperfecta type 3 (AI3) [MIM:130900]. AI3 is an autosomal dominant hypomineralized form of amelogenesis imperfecta, a defect of enamel formation. AI3 is characterized by enamel of normal thickness, but soft and with cheesy consistency. Enamel is lost from tooth soon after eruption.
  • Sequence similarities
    Belongs to the FAM83 family.
  • Information by UniProt
  • Database links
  • Alternative names
    • AI3 antibody
    • FA83H_HUMAN antibody
    • Fam83h antibody
    • Family with sequence similarity 83 member H antibody
    • Protein FAM83H antibody
    see all

Images

  • Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells)
    Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells)
  • ab121816, at 1/15 dilution, staining FAM83H in paraffin-embedded Human vagina tissue by Immunohistochemistry.
  • All lanes : Anti-FAM83H antibody (ab121816) at 1/250 dilution

    Lane 1 : RT-4 cell lysate
    Lane 2 : U-251 MG cell lysate
    Lane 3 : Human Plasma lysate
    Lane 4 : Human Liver lysate
    Lane 5 : Human Tonsil lysate
  • Immunohistochemical staining of Human vagina shows moderate cytoplasmic positivity in squamous epithelial cells using ab121816

References

ab121816 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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