Overview

  • Product name
  • Description
    Rabbit polyclonal to FAM83H
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: VVSQAWREEV AAPGAVGGER RSLESCLLDL RDSFAQQLHQ EAERQPGAAS LTAAQLLDTL GRSGSDRLPS RFLSAQSHST SPQGLDSPLP LEGS, corresponding to amino acids 764-857 of Human FAM83H (UniProt ID: Q6ZRV2).

  • Positive control
    • Human vagina tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab121828 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/250 - 1/500.
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    May play a major role in the structural organization and calcification of developing enamel.
  • Tissue specificity
    Expressed in the tooth follicle.
  • Involvement in disease
    Defects in FAM83H are the cause of amelogenesis imperfecta type 3 (AI3) [MIM:130900]. AI3 is an autosomal dominant hypomineralized form of amelogenesis imperfecta, a defect of enamel formation. AI3 is characterized by enamel of normal thickness, but soft and with cheesy consistency. Enamel is lost from tooth soon after eruption.
  • Sequence similarities
    Belongs to the FAM83 family.
  • Information by UniProt
  • Database links
  • Alternative names
    • AI3 antibody
    • FA83H_HUMAN antibody
    • Fam83h antibody
    • Family with sequence similarity 83 member H antibody
    • Protein FAM83H antibody
    see all

Anti-FAM83H antibody images

  • ab121828, at a 1/200 dilution, staining FAM83H in paraffin embedded Human vagina tissue by Immunohistochemistry.
  • Immunohistochemical staining of Human vagina shows strong cytoplasmic and nuclear positivity in squamous epithelial cells using ab121828

References for Anti-FAM83H antibody (ab121828)

ab121828 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab121828.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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