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ab2187 has been referenced in 27 publications.

  • Luebben SW  et al. A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression. Nucleic Acids Res 42:5605-15 (2014). WB, ICC, IHC ; Mouse . PubMed: 24589582
  • Yeo JE  et al. CtIP mediates replication fork recovery in a FANCD2-regulated manner. Hum Mol Genet N/A:N/A (2014). PubMed: 24556218
  • Muñoz MC  et al. An RNF168 fragment defective for focal accumulation at DNA damage is proficient for inhibition of homologous recombination in BRCA1 deficient cells. Nucleic Acids Res 42:7720-33 (2014). WB . PubMed: 24829461
  • Bryant C  et al. Chk1 inhibition as a novel therapeutic strategy for treating triple-negative breast and ovarian cancers. BMC Cancer 14:570 (2014). WB . PubMed: 25104095
  • Renaud E & Rosselli F FANC pathway promotes UV-induced stalled replication forks recovery by acting both upstream and downstream Pol? and Rev1. PLoS One 8:e53693 (2013). ICC/IF ; Human . PubMed: 23365640
  • Naim V  et al. ERCC1 and MUS81-EME1 promote sister chromatid separation by processing late replication intermediates at common fragile sites during mitosis. Nat Cell Biol 15:1008-15 (2013). PubMed: 23811686
  • Luebben SW  et al. Helq acts in parallel to Fancc to suppress replication-associated genome instability. Nucleic Acids Res N/A:N/A (2013). PubMed: 24005041
  • Uringa EJ  et al. RTEL1 contributes to DNA replication and repair and telomere maintenance. Mol Biol Cell 23:2782-92 (2012). ICC/IF ; Mouse . PubMed: 22593209
  • Cherubini G  et al. The FANC pathway is activated by adenovirus infection and promotes viral replication-dependent recombination. Nucleic Acids Res : (2011). WB, ICC/IF ; Human . PubMed: 21421559
  • Baldeyron C  et al. HP1{alpha} recruitment to DNA damage by p150CAF-1 promotes homologous recombination repair. J Cell Biol 193:81-95 (2011). ICC/IF ; Human . PubMed: 21464229
  • Guervilly JH  et al. USP1 deubiquitinase maintains phosphorylated CHK1 by limiting its DDB1-dependent degradation. Hum Mol Genet 20:2171-81 (2011). WB, ICC/IF ; Human . PubMed: 21389083
  • MacKay C  et al. Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2. Cell 142:65-76 (2010). WB ; Human . PubMed: 20603015
  • Raya A  et al. Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells. Nature 460:53-9 (2009). ICC/IF ; Human . PubMed: 19483674
  • Naim V & Rosselli F The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities. Nat Cell Biol 11:761-8 (2009). ICC/IF ; Human . PubMed: 19465921
  • Jacome A  et al. Lentiviral-mediated genetic correction of hematopoietic and mesenchymal progenitor cells from Fanconi anemia patients. Mol Ther 17:1083-92 (2009). ICC/IF ; Human . PubMed: 19277017
  • Deans AJ & West SC FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia. Mol Cell 36:943-53 (2009). WB ; Human . PubMed: 20064461
  • Wilson JB  et al. FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3. Oncogene 27:3641-52 (2008). WB, IP . PubMed: 18212739
  • Guervilly JH  et al. Loss of CHK1 function impedes DNA damage-induced FANCD2 monoubiquitination but normalizes the abnormal G2 arrest in Fanconi anemia. Hum Mol Genet 17:679-89 (2008). PubMed: 18029388
  • Briot D  et al. Aberrant activation of stress-response pathways leads to TNF-alpha oversecretion in Fanconi anemia. Blood 111:1913-23 (2008). PubMed: 18055871
  • Bogliolo M  et al. Histone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain chromosome stability. EMBO J 26:1340-51 (2007). ICC/IF ; Human . PubMed: 17304220
  • Hirano S  et al. Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM. EMBO J 24:418-27 (2005). PubMed: 15616572
  • Pichierri P & Rosselli F The DNA crosslink-induced S-phase checkpoint depends on ATR-CHK1 and ATR-NBS1-FANCD2 pathways. EMBO J 23:1178-87 (2004). PubMed: 14988723
  • Hussain S  et al. Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways. Hum Mol Genet 13:1241-8 (2004). PubMed: 15115758
  • Taniguchi T  et al. Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors. Nat Med 9:568-74 (2003). PubMed: 12692539
  • Taniguchi T  et al. S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51. Blood 100:2414-20 (2002). PubMed: 12239151
  • Howlett NG  et al. Biallelic inactivation of BRCA2 in Fanconi anemia. Science 297:606-9 (2002). PubMed: 12065746
  • Ahmad SI  et al. Molecular biology of Fanconi anaemia--an old problem, a new insight. Bioessays 24:439-48 (2002). PubMed: 12001267