Overview

  • Product name
  • Description
    Mouse polyclonal to FANCF
  • Host species
    Mouse
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein corresponding to amino acids 1-374 of Human FANCF (NP_073562.1)

  • Positive control
    • FANCF transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab168735 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 42 kDa.

Target

  • Function
    DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.
  • Involvement in disease
    Defects in FANCF are a cause of Fanconi anemia (FA) [MIM:227650]. FA is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • A730016A17 antibody
    • FACF antibody
    • FAF antibody
    • FANCF antibody
    • FANCF_HUMAN antibody
    • Fanconi anemia complementation group F antibody
    • Fanconi anemia group F protein antibody
    • MGC126856 antibody
    • Protein FACF antibody
    • RGD1561456 antibody
    see all

Images

  • All lanes : Anti-FANCF antibody (ab168735) at 1 µg/ml

    Lane 1 : FANCF transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 15 µl per lane.

    Secondary
    All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugated secondary antibody at 1/2500 dilution

    Predicted band size: 42 kDa

References

ab168735 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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