Overview

  • Product nameAnti-Fascin 2 antibody
    See all Fascin 2 primary antibodies
  • Description
    Rabbit polyclonal to Fascin 2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within internal amino acids 235-284 (AGTLKAGRNT RPGKDELFDL EESHPQVVLV AANHRYVSVR QGVNVSANQD) of Human Fascin 2 (NP_001070650).

  • Positive control
    • Human fetal brain lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab111601 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.2 - 1 µg/ml. Predicted molecular weight: 57 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionActs as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as disk morphogenesis.
  • Tissue specificityLocalized specifically in the outer and inner segments of the photoreceptor cells in the retina.
  • Involvement in diseaseDefects in FSCN2 are the cause of retinitis pigmentosa type 30 (RP30) [MIM:607921]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP30 inheritance is autosomal dominant.
  • Sequence similaritiesBelongs to the fascin family.
  • Cellular localizationCytoplasm > cytoskeleton. Cell projection > stereocilium.
  • Information by UniProt
  • Database links
  • Alternative names
    • Fascin homolog 2, actin bundling protein, retinal Strongylocentrotus purpuratus antibody
    • Fascin Strongylocentrotus purpuratus homolog 2 actin bundling protein, retinal antibody
    • Fascin-2 antibody
    • FSCN2 antibody
    • FSCN2_HUMAN antibody
    • Retinal fascin antibody
    • RFSN antibody
    • RP30 antibody
    see all

Anti-Fascin 2 antibody images

  • Anti-Fascin 2 antibody (ab111601) at 0.25 µg/ml + Human fetal brain lysate at 10 µg

    Predicted band size : 57 kDa

References for Anti-Fascin 2 antibody (ab111601)

ab111601 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"