Anti-Fascin antibody [EPR2681] (ab108607)


  • Product nameAnti-Fascin antibody [EPR2681]
    See all Fascin primary antibodies
  • Description
    Rabbit monoclonal [EPR2681] to Fascin
  • Tested applicationsSuitable for: WB, Flow Cytmore details
    Unsuitable for: ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to internal sequence amino acids 435-460 of Human Fascin

  • Positive control
    • HeLa, SH-SY5Y and K-562 cell lysates
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.



Our Abpromise guarantee covers the use of ab108607 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 55 kDa.
Flow Cyt 1/500 - 1/1000. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • Application notesIs unsuitable for ICC,IHC-P or IP.
  • Target

    • FunctionOrganizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration.
    • Tissue specificityUbiquitous.
    • Sequence similaritiesBelongs to the fascin family.
    • DomainComposed of four beta-trefoil domains.
    • Post-translational
      Phosphorylation on Ser-39 inhibits the actin-binding ability of fascin.
    • Cellular localizationCytoplasm > cytoskeleton. Cell projection > filopodium. Cell projection > invadopodium.
    • Information by UniProt
    • Database links
    • Alternative names
      • 55 kDa actin bundling protein antibody
      • 55 kDa actin-bundling protein antibody
      • Actin bundling protein antibody
      • actin bundling protein, 55-KD antibody
      • FAN 1 antibody
      • FAN1 antibody
      • Fascin 1 antibody
      • Fascin actin bundling protein 1 antibody
      • Fascin antibody
      • Fascin homolog 1 actin bundling protein (Strongylocentrotus purpuratus) antibody
      • Fascin homolog 1 antibody
      • Fascin, sea urchin, homolog of, 1 antibody
      • Fascin1 antibody
      • FLJ38511 antibody
      • FSCN 1 antibody
      • FSCN1 antibody
      • FSCN1_HUMAN antibody
      • HSN antibody
      • p55 antibody
      • Singed (Drosophila) like (sea urchin fascin homolog like) antibody
      • Singed drosophila homolog like antibody
      • Singed like (fascin homolog sea urchin) (Drosophila) antibody
      • Singed like (fascin homolog sea urchin) antibody
      • Singed like protein antibody
      • Singed, drosophila, homolog of antibody
      • Singed-like protein antibody
      • SNL antibody
      • Strongylocentrotus purpuratus antibody
      see all

    Anti-Fascin antibody [EPR2681] images

    • All lanes : Anti-Fascin antibody [EPR2681] (ab108607) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : SH-SY5Y cell lysate
      Lane 3 : K562 cell lysate

      Lysates/proteins at 10 µg per lane.

      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 55 kDa
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References for Anti-Fascin antibody [EPR2681] (ab108607)

    ab108607 has not yet been referenced specifically in any publications.

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