Anti-Fast Myosin Skeletal Heavy chain antibody [MYSN02], prediluted (ab75370)

Overview

  • Product name
    Anti-Fast Myosin Skeletal Heavy chain antibody [MYSN02], prediluted
    See all Fast Myosin Skeletal Heavy chain primary antibodies
  • Description
    Mouse monoclonal [MYSN02] to Fast Myosin Skeletal Heavy chain, prediluted
  • Specificity
    ab75370 may be used for detecting cross striated muscle differentiation in tumors. It will not stain human or animal cardiac muscle, smooth muscle myosin, or cells grown by tissue culture (non muscle myosin).
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Rabbit, Chicken, Guinea pig, Cow, Human
  • Immunogen

    Rabbit muscle myosin

  • Positive control
    • Human skeletal muscle tissue.
  • General notes

    Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.

Properties

Applications

Our Abpromise guarantee covers the use of ab75370 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notes
    IHC-P: Ready to use.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Muscle contraction.
    • Sequence similarities
      Contains 1 IQ domain.
      Contains 1 myosin head-like domain.
    • Domain
      The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4 heptapeptides, characteristic for alpha-helical coiled coils.
      Each myosin heavy chain can be split into 1 light meromyosin (LMM) and 1 heavy meromyosin (HMM). It can later be split further into 2 globular subfragments (S1) and 1 rod-shaped subfragment (S2).
    • Cellular localization
      Cytoplasm > myofibril. Thick filaments of the myofibrils.
    • Information by UniProt
    • Database links
    • Alternative names
      • adult 1 antibody
      • MYH1 antibody
      • MYH1_HUMAN antibody
      • MyHC-2x antibody
      • MyHC-IIx/d antibody
      • Myosin heavy chain 1 antibody
      • Myosin heavy chain 2x antibody
      • Myosin heavy chain antibody
      • Myosin heavy chain IIx/d antibody
      • Myosin-1 antibody
      • skeletal muscle antibody
      see all

    Anti-Fast Myosin Skeletal Heavy chain antibody [MYSN02], prediluted images

    • ab75370 staining Fast Myosin Skeletal Heavy chain in formalin fixed, paraffin embedded human skeletal muscle tissue by Immunohistochemistry, using peroxidase conjugate and AEC chromogen. Note cytoplasmic staining of muscle cells.

    References for Anti-Fast Myosin Skeletal Heavy chain antibody [MYSN02], prediluted (ab75370)

    This product has been referenced in:
    • Lundgreen K  et al. Lower muscle regenerative potential in full-thickness supraspinatus tears compared to partial-thickness tears. Acta Orthop 84:565-70 (2013). IHC-P ; Human . Read more (PubMed: 24171689) »

    See 1 Publication for this product

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    There are currently no Abreviews or Questions for ab75370.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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