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Rabbit polyclonal to FAT
Predicted to work with:
Synthetic peptide within Human FAT aa 4450-4500. The exact sequence is proprietary. NP_005236.2
HeLa, 293T, Jurkat, NIH 3T3 and TCMK-1 whole cell lysates
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Preservative: 0.09% Sodium azide
Constituent: 99% Tris citrate/phosphate pH 7 to 8
Concentration information loading...
Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/2000 - 1/10000. Predicted molecular weight: 506 kDa.
Plays an essential role for cellular polarization, directed cell migration and modulating cell-cell contact.
Expressed in many epithelial and some endothelial and smooth muscle cells.
Contains 33 cadherin domains.
Contains 5 EGF-like domains. Contains 1 laminin G-like domain.
A PTB-like motif (DNXYH sequence) is required for the targeting to the leading edge. This motif represents a minimal protein-protein interaction core motif that is not regulated by tyrosine phosphorylation.
Undergoes proteolytic cleavage. The extracellular domain is cleaved off and the cytoplasmic domain (about 400 AA) shuttles to the nucleus.
Cell membrane. Nucleus. Cytoplasm > perinuclear region.
Information by UniProt
Cadherin family member 7 antibody
Cadherin family member 7 precursor antibody
Cadherin ME5 antibody
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"