Overview

  • Product name
  • Description
    Mouse polyclonal to FATP1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length human SLC27A1 protein (NP_940982).

  • Positive control
    • SLC27A1 transfected 293T lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab69458 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 71 kDa (predicted molecular weight: 71 kDa).

Target

  • Relevance
    SLC27A1 (Solute carrier family 27 member 1) is involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. SLC27A1 may act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. It also plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis and may be involved in regulation of cholesterol metabolism.
  • Cellular localization
    Cell membrane; Single-pass membrane protein. Intracytoplasmic membrane; Single-pass membrane protein. Cytoplasm. Note=Plasma membrane and intracellular membranes, at least in adipocytes. Predominantly cytoplasmic in myocytes.
  • Database links
  • Alternative names
    • ACSVL5 antibody
    • FATP 1 antibody
    • FATP antibody
    • FATP1 antibody
    • Fatty acid transport protein 1 antibody
    • FLJ00336 antibody
    • Long chain fatty acid transport protein 1 antibody
    • MGC71751 antibody
    • SLC27A1 antibody
    • Solute carrier family 27 (fatty acid transporter) member 1 antibody
    • Solute carrier family 27 member 1 antibody
    see all

Images

  • All lanes : Anti-FATP1 antibody (ab69458) at 1/500 dilution

    Lane 1 : SLC27A1 transfected 293T lysate
    Lane 2 : Non-transfected 293T lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 71 kDa
    Observed band size : 71 kDa

References

This product has been referenced in:
  • Liu Z  et al. Adiponectin reduces ER stress-induced apoptosis through PPARa transcriptional regulation of ATF2 in mouse adipose. Cell Death Dis 7:e2487 (2016). WB . Read more (PubMed: 27882945) »
  • Duan Y  et al. n-6:n-3 PUFA ratio is involved in regulating lipid metabolism and inflammation in pigs. Br J Nutr 111:445-51 (2014). Read more (PubMed: 23947577) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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