• Product name
  • Description
    Rabbit polyclonal to FBP2
  • Specificity
    The immunogen for this antibody has 84% alignment with the FBP1 protein. It is therefore likely that this antibody could detect FBP1 as well as FBP2.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Saccharomyces cerevisiae, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 216-265 (YAKYFDAATT EYVQKKKFPE DGSAPYGARY VGSMVADVHR TLVYGGIFLY) of Human FBP2 (NP_003828).

  • Positive control
    • Human fetal muscle lysate.



Our Abpromise guarantee covers the use of ab84566 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 37 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • Function
    Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate.
  • Tissue specificity
    Expressed in skeletal muscle (at protein level).
  • Pathway
    Carbohydrate biosynthesis; gluconeogenesis.
  • Sequence similarities
    Belongs to the FBPase class 1 family.
  • Cellular localization
    Cell junction. Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere, Z line. In neonatal cardiomyocytes, distributed throughout the cytosol, accumulating in the intercalated disks which occur at the Z line of cardiomyocytes and connect adjacent cells, and also located in the nucleus; dissociates from the Z line following an increase in cytosolic Ca(2+) concentration (By similarity). In muscle precursor cells, localizes predominantly to the nucleus and to a lesser extent to the cytoplasm at the proliferative phase, while mainly localizing to the cytoplasm at the differentiation phase (By similarity). Colocalizes with ALDOA and alpha-actinin on both sides of the Z line of skeletal muscle; dissociates rapidly from the Z line following an increase in cytosolic Ca(2+) concentration.
  • Information by UniProt
  • Database links
  • Alternative names
    • 6-bisphosphatase isozyme 2 antibody
    • 6-bisphosphate 1-phosphohydrolase 2 antibody
    • D fructose 1 6 bisphosphate 1 phosphohydrolase 2 antibody
    • D-fructose-1 antibody
    • F16P2_HUMAN antibody
    • FBP 2 antibody
    • fbp2 antibody
    • FBPase 2 antibody
    • FBPase antibody
    • fructose 1 6 bisphosphatase 2 antibody
    • Fructose 1 6 bisphosphatase isozyme 2 antibody
    • Fructose-1 antibody
    • Hexosediphosphatase antibody
    • MGC142192 antibody
    • Muscle FBPase antibody
    • Muscle fructose bisphosphatase antibody
    see all


  • Anti-FBP2 antibody (ab84566) at 1 µg/ml (in 5% skim milk / PBS buffer) + human fetal muscle lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 37 kDa
    Observed band size : 37 kDa


ab84566 has not yet been referenced specifically in any publications.

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