Overview

  • Product nameAnti-FBXL3 antibody
    See all FBXL3 primary antibodies
  • Description
    Rabbit polyclonal to FBXL3
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Sheep, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Human, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within C-terminal amino acids 239-288 (ELLLALSSEK HVRLEHLRID VVSENPGQTH FHTIQKSSWD AFIKHSPKVN) of Mouse FBXL3 (NP_056637).

  • Positive control
    • Mouse kidney lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab123116 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 49 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionSubstrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation.
  • Tissue specificityWidely expressed.
  • Sequence similaritiesContains 1 F-box domain.
    Contains 7 LRR (leucine-rich) repeats.
  • Cellular localizationNucleus. Cytoplasm. Predominantly nuclear.
  • Information by UniProt
  • Database links
  • Alternative names
    • F box and leucine rich repeat protein 3 antibody
    • F box and leucine rich repeat protein 3A antibody
    • F box protein Fbl3a antibody
    • F-box and leucine-rich repeat protein 3A antibody
    • F-box/LRR-repeat protein 3 antibody
    • F-box/LRR-repeat protein 3A antibody
    • FBL3 antibody
    • FBL3A antibody
    • Fbxl3 antibody
    • FBXL3_HUMAN antibody
    • FBXL3A antibody
    see all

Anti-FBXL3 antibody images

  • Anti-FBXL3 antibody (ab123116) at 1 µg/ml + Mouse kidney lysate at 10 µg

    Predicted band size : 49 kDa

References for Anti-FBXL3 antibody (ab123116)

ab123116 has not yet been referenced specifically in any publications.

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