Overview

  • Product nameAnti-FBXL3 antibody
    See all FBXL3 primary antibodies
  • Description
    Goat polyclonal to FBXL3
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Dog
  • Immunogen

    Synthetic peptide:

    C-KRGGRDSDRNSSEE

    , corresponding to N terminal amino acids 2-15 of Human FBXL3

  • Positive control
    • Human Adipose lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab53516 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesPeptide ELISA: antibody detection limit dilution 1:32,000.

    WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 53 kDa (predicted molecular weight: 49 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionSubstrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation.
    • Tissue specificityWidely expressed.
    • Sequence similaritiesContains 1 F-box domain.
      Contains 7 LRR (leucine-rich) repeats.
    • Cellular localizationNucleus. Cytoplasm. Predominantly nuclear.
    • Information by UniProt
    • Database links
    • Alternative names
      • F box and leucine rich repeat protein 3 antibody
      • F box and leucine rich repeat protein 3A antibody
      • F box protein Fbl3a antibody
      • F-box and leucine-rich repeat protein 3A antibody
      • F-box/LRR-repeat protein 3 antibody
      • F-box/LRR-repeat protein 3A antibody
      • FBL3 antibody
      • FBL3A antibody
      • Fbxl3 antibody
      • FBXL3_HUMAN antibody
      • FBXL3A antibody
      see all

    Anti-FBXL3 antibody images

    References for Anti-FBXL3 antibody (ab53516)

    ab53516 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"