For the best experience on the Abcam website please upgrade to a modern browser such as
Product name Anti-FBXL3 antibody See all FBXL3 primary antibodies
Goat polyclonal to FBXL3
Tested applications Suitable for:
WB more details
Predicted to work with:
C-KRGGRDSDRNSSEE , corresponding to N terminal amino acids 2-15 of Human FBXL3
Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris saline, pH 7.3
Concentration information loading...
Purity Immunogen affinity purified
Purification notes Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notes Peptide ELISA: antibody detection limit dilution 1:32,000.
WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 53 kDa (predicted molecular weight: 49 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Function Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation.
Tissue specificity Widely expressed.
Sequence similarities Contains 1 F-box domain. Contains 7 LRR (leucine-rich) repeats.
Cellular localization Nucleus. Cytoplasm. Predominantly nuclear.
Information by UniProt
F box and leucine rich repeat protein 3 antibody
F box and leucine rich repeat protein 3A antibody
F box protein Fbl3a antibody
Anti-FBXL3 antibody images
References for Anti-FBXL3 antibody (ab53516)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"