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Rabbit polyclonal to FBXL3
Predicted to work with:
Mouse, Rat, Cow, Zebrafish
Recombinant protein fragment corresponding to a region within amino acids 14 and 279 of Human FBXL3 (NP_036290).
293T, H1299, HeLa, HepG2 and Raji cell lines. MOLT4 whole cell lysate and A431 cells
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
Concentration information loading...
Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 49 kDa.
1/100 - 1/200.
Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation.
Contains 1 F-box domain.
Contains 7 LRR (leucine-rich) repeats.
Nucleus. Cytoplasm. Predominantly nuclear.
Information by UniProt
F box and leucine rich repeat protein 3 antibody
F box and leucine rich repeat protein 3A antibody
F box protein Fbl3a antibody
Western blot - Anti-FBXL3 antibody (ab96645)
Anti-FBXL3 antibody (ab96645) at 1/1000 dilution + MOLT4 whole cell lysate at 30 µg
Predicted band size: 49 kDa 10% SDS PAGE
Immunocytochemistry/ Immunofluorescence - Anti-FBXL3 antibody (ab96645)
ab96645, at a 1/200 dilution, staining FBXL3 in paraformaldehyde fixed A431 by Immunofluorescence analysis. Lower image merged with DNA probe.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"