Overview

  • Product nameAnti-FBXO11 antibody
    See all FBXO11 primary antibodies
  • Description
    Rabbit polyclonal to FBXO11
  • Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide, derived from an internal sequence of FBXO11 (UniProt ID: Q86XK2).

Properties

Applications

Our Abpromise guarantee covers the use of ab110965 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 104 kDa.
ELISA Use at an assay dependent concentration.
IHC-P 1/100 - 1/1000.

Target

  • FunctionSubstrate recognition component of the a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Binds to and neddylates phosphorylated p53/TP53, inhibiting its transcriptional activity. SCF(FBXO11) does not seem to direct ubiquitination of TP53.
  • Tissue specificityIsoform 5 is expressed in keratinocytes, fibroblasts and melanocytes.
  • PathwayProtein modification; protein ubiquitination.
  • Sequence similaritiesContains 1 F-box domain.
    Contains 19 PbH1 repeats.
    Contains 1 UBR-type zinc finger.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • F box protein 11 antibody
    • F-box only protein 11 antibody
    • FBX11 antibody
    • FBX11_HUMAN antibody
    • Fbxo11 antibody
    • PRMT9 antibody
    • Protein arginine N methyltransferase 9 antibody
    • Ubiquitin protein ligase E3 component n recognin 6 antibody
    • UBR6 antibody
    • UG063H01 antibody
    • VIT-1 antibody
    • VIT1 antibody
    • Vitiligo associated protein VIT 1 antibody
    • Vitiligo-associated protein 1 antibody
    see all

References for Anti-FBXO11 antibody (ab110965)

ab110965 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab110965.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"