Overview

  • Product name
  • Description
    Rabbit polyclonal to FBXO2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 234-296 of Human FBXO2 (NP_036300)

  • Positive control
    • A431, HepG2 cell lysate and H1299 whole cell lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 1X PBS, pH 7.0
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab96391 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 33 kDa.

Target

  • Function
    Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type.
  • Pathway
    Protein modification; protein ubiquitination.
  • Sequence similarities
    Contains 1 F-box domain.
    Contains 1 FBA (F-box associated) domain.
  • Cellular localization
    Cytoplasm. Microsome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • F box gene 1 antibody
    • F box only protein 2 antibody
    • F box protein 2 antibody
    • F box protein only 2 antibody
    • F-box only protein 2 antibody
    • FBG 1 antibody
    • FBG1 antibody
    • Fbs 1 antibody
    • Fbs1 antibody
    • Fbs2 antibody
    • FBX 2 antibody
    • FBX2 antibody
    • FBX2_HUMAN antibody
    • FBXO 2 antibody
    • FBXO2 antibody
    • Neural F box protein NFB42 antibody
    • Neural F-box protein, 42-KD, rat, homolog of antibody
    • NFB 42 antibody
    • NFB42 antibody
    • OCP1 antibody
    • organ of Corti protein 1 antibody
    • Prpl4 antibody
    see all

Images

  • Anti-FBXO2 antibody (ab96391) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

    Predicted band size : 33 kDa

References

ab96391 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab96391.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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