Overview

  • Product nameAnti-FBXO2 antibody
    See all FBXO2 primary antibodies
  • Description
    Rabbit polyclonal to FBXO2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 234-296 of Human FBXO2 (NP_036300)

  • Positive control
    • A431, HepG2 cell lysate and H1299 whole cell lysate.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab96391 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 33 kDa.

Target

  • FunctionSubstrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type.
  • PathwayProtein modification; protein ubiquitination.
  • Sequence similaritiesContains 1 F-box domain.
    Contains 1 FBA (F-box associated) domain.
  • Cellular localizationCytoplasm. Microsome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • F box gene 1 antibody
    • F box only protein 2 antibody
    • F box protein 2 antibody
    • F box protein only 2 antibody
    • F-box only protein 2 antibody
    • FBG 1 antibody
    • FBG1 antibody
    • Fbs 1 antibody
    • Fbs1 antibody
    • Fbs2 antibody
    • FBX 2 antibody
    • FBX2 antibody
    • FBX2_HUMAN antibody
    • FBXO 2 antibody
    • FBXO2 antibody
    • Neural F box protein NFB42 antibody
    • Neural F-box protein, 42-KD, rat, homolog of antibody
    • NFB 42 antibody
    • NFB42 antibody
    • OCP1 antibody
    • organ of Corti protein 1 antibody
    • Prpl4 antibody
    see all

Anti-FBXO2 antibody images

  • Anti-FBXO2 antibody (ab96391) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

    Predicted band size : 33 kDa

References for Anti-FBXO2 antibody (ab96391)

ab96391 has not yet been referenced specifically in any publications.

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