Overview

  • Product nameAnti-FBXO25 antibody
    See all FBXO25 primary antibodies
  • Description
    Mouse monoclonal to FBXO25
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-368 of Human FBXO25

Properties

Applications

Our Abpromise guarantee covers the use of ab57051 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionSubstrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT).
    • Tissue specificityExpressed in all brain tissue observed.
    • PathwayProtein modification; protein ubiquitination.
    • Involvement in diseaseNote=A chromosomal aberration involving FBXO25 is a cause of X-linked mental retardation (XLMR). Translocation t(X;8)(p11.22;p23.3) with SHROOM4.
    • Sequence similaritiesContains 1 F-box domain.
    • DomainThe F-box is necessary for the interaction with SKP1.
    • Cellular localizationNucleus. In the nucleus, associates with a subnuclear dot-like structure. Colocalized with SKP1.
    • Information by UniProt
    • Database links
    • Alternative names
      • F box only protein 25 antibody
      • F box protein 25 antibody
      • F box protein Fbx25 antibody
      • F-box only protein 25 antibody
      • FBX25 antibody
      • FBX25_HUMAN antibody
      • FBXO25 antibody
      • MGC20256 antibody
      • MGC51975 antibody
      • OTTHUMP00000115399 antibody
      see all

    Anti-FBXO25 antibody images



    • Predicted band size : 43 kDa
      FBXO25 antibody (ab57051) at 1ug/lane + COLO cell lysate at 25ug/lane.

    References for Anti-FBXO25 antibody (ab57051)

    ab57051 has not yet been referenced specifically in any publications.

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