Overview

  • Product nameAnti-FBXO7 antibody
    See all FBXO7 primary antibodies
  • Description
    Mouse monoclonal to FBXO7
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: AVCRDLFTAS NDPLLWRFLY LRDFRDNTVR VQDTDWKELY RKRHIQRKES PKGRFVMLLP SSTHTIPFYP NPLHPRPFPS SRLPPGIIGG EYDQRPTLP, corresponding to amino acids 357-456 of Human FBXO7

Properties

Applications

Our Abpromise guarantee covers the use of ab57037 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionSubstrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5.
    • PathwayProtein modification; protein ubiquitination.
    • Involvement in diseaseDefects in FBXO7 are the cause of Parkinson disease type 15 (PARK15) [MIM:260300]; also known as parkinsonian-pyramidal syndrome. A neurodegenerative disorder characterized by parkinsonian and pyramidal signs. Clinical manifestations include tremor, bradykinesia, rigidity, postural instability, spasticity, mainly in the lower limbs, and hyperreflexia.
    • Sequence similaritiesContains 1 F-box domain.
    • Cellular localizationCytoplasm. Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • F box only protein 7 antibody
      • F box protein 7 antibody
      • F-box only protein 7 antibody
      • FBX antibody
      • FBX07 antibody
      • FBX7 antibody
      • FBX7_HUMAN antibody
      • Fbxo7 antibody
      • PARK15 antibody
      • PKPS antibody
      see all

    Anti-FBXO7 antibody images

    • Western blot against tagged recombinant protein immunogen using ab57037 FBXO7 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    References for Anti-FBXO7 antibody (ab57037)

    ab57037 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab57037.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"