Anti-Fc epsilon RI antibody [CRA2] (FITC) (ab122891)

Overview

• Product name
  Anti-Fc epsilon RI antibody [CRA2] (FITC)
  See all Fc epsilon RI primary antibodies
• Description
  Mouse monoclonal [CRA2] to Fc epsilon RI (FITC)
• Conjugation
  FITC. Ex: 493nm, Em: 528nm
• Tested applications
  Suitable for: ICC, Flow Cyt, Inhibition Assaymore details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Recombinant fragment: FEDSGEYKCQ HQQVNESEPV YLEVFSDWLL LQASAEVVME GQPLFLRCHG WRNWDVYKVI YYKDGEALKY WYENHNISIT NATVEDSG, corresponding to amino acids 85-172 of Human Fc epsilon RI

  Run BLAST with Run BLAST with
• Epitope
  Amino acids 85-172 of Fc epsilon RI
• Positive control
  • CHO/alpha beta gamma cells
• General notes

  [FITC]/[IgG] 8.9

Properties

• Form
  Liquid
• Storage instructions
  Shipped at 4°C. Store at +4°C.
• Storage buffer
  pH: 7.40
  Constituents: 49% PBS, 50% Glycerol
• Concentration information loading...
• Purity
  IgG fraction
• Purification notes
  ab122891 was purified from serum free culture medium of mouse hybridoma (CRA2) by propriety chromatography under mild conditions. Filter sterilized
• Clonality
  Monoclonal
• Clone number
  CRA2
• Isotype
  IgG1
• Light chain type
  kappa
• Research areas
  • Immunology
  • Immunoglobulins
  • Receptors

  • Immunology
  • Immunoglobulins
  • Heavy Chain
  • IgE

Associated products

• Compatible Secondaries
  • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
  • Goat Anti-Mouse IgG H&L (HRP) (ab205719)
• Related Products
  • Anti-Fc epsilon RI antibody [CRA1] (Biotin) (ab122882)

Applications

Target

• Function
  Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
• Sequence similarities
  Contains 2 Ig-like (immunoglobulin-like) domains.
• Cellular localization
  Cell membrane.

• Target information above from: UniProt accession P12319 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 2205 Human
  • Omim: 147140 Human
  • SwissProt: P12319 Human
  • Unigene: 897 Human
• Alternative names
  • Fc epsilon RI alpha antibody
  • Fc epsilon RI alpha chain antibody
  • Fc epsilon RI alpha-chain antibody

  • Fc fragment of IgE high affinity I receptor for alpha polypeptide antibody
  • Fc fragment of IgE, high affinity I, receptor for, alpha subunit antibody
  • Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide antibody
  • Fc IgE receptor alpha polypeptide antibody
  • Fc IgE receptor, alpha chain antibody
  • Fc IgE receptor, alpha polypeptide antibody
  • Fc of IgE high affinity I receptor for alpha polypeptide antibody
  • Fc-epsilon RI-alpha antibody
  • FCE 1A antibody
  • FCE1A antibody
  • FCER 1A antibody
  • Fcer1a antibody
  • FCERA_HUMAN antibody
  • FceRI alpha antibody
  • FcERI antibody
  • high affinity IgE receptor antibody
  • High affinity immunoglobulin epsilon receptor alpha subunit antibody
  • high affinity immunoglobulin epsilon receptor alpha-subunit antibody
  • High affinity immunoglobulin epsilon receptor subunit alpha antibody
  • IgE Fc receptor alpha subunit antibody
  • IgE Fc receptor subunit alpha antibody
  • Immunoglobulin E receptor high affinity of mast cells alpha polypeptide antibody
  • immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide antibody

  see all

Protocols

• Flow cytometry protocols
• Immunocytochemistry & immunofluorescence protocols