Overview

  • Product name
  • Description
    Rabbit polyclonal to FCN3
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Horse, Chicken, Cow, Cat, Pig, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 35-84 (LEASKVVLLP SCPGAPGSPG EKGAPGPQGP PGPPGKMGPK GEPGDPVNLL) of Human FCN3 (NP_003656).

  • Positive control
    • ACHN cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab98136 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 33 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Relevance
    FCN3 (Ficolin 3) is involved in the serum exerting lectin activity. In human serum, there are two types of ficolins, both of which have lectin activity. FCN3 is a thermolabile beta 2 macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. It can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway.
  • Cellular localization
    Secreted. Note: Found in blood plasma, bronchus, alveolus and bile duct.
  • Database links
  • Alternative names
    • Collagen/fibrinogen domain containing lectin 3 p35 antibody
    • Collagen/fibrinogen domain containing protein 3 antibody
    • FCN 3 antibody
    • FCNH antibody
    • Ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen) antibody
    • Ficolin (collagen/fibrinogen domain containing) 3 antibody
    • Ficolin 3 antibody
    • H ficolin antibody
    • HAKA1 antibody
    • Hakata antigen antibody
    • MGC22543 antibody
    see all

Images

  • Anti-FCN3 antibody (ab98136) at 1 µg/ml (in 5% skim milk / PBS buffer) + ACHN cell lysate at 10 µg

    Predicted band size : 33 kDa

References

ab98136 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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